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Table 3 Multivariable competing risk Fine-Gray regression models for first healthcare-associated infection (HAI, Model 1) or first device-related healthcare-associated infection (first dr-HAI, Model 2) among the patients admitted to the main Intensive Care Unit (ICU) of Umberto I teaching hospital of Rome between 1st March and 4th April 2019 and 1st March and 4th April 2020

From: The impact of the COVID-19 pandemic on healthcare-associated infections in intensive care unit patients: a retrospective cohort study

  HAI (model 1) dr-HAI (model 2)
SHR (95% CI) p value SHR (95% CI) p value
Year of admission to the ICU (2020) 2.66 (1.31–5.38) 0.007 10.0 (1.84–54.41) 0.008
Sex (female) 0.93 (0.47–1.85) 0.835 0.77 (0.30–1.99) 0.585
Age (years) 0.97 (0.96–0.99) 0.006 0.97 (0.94–0.99) 0.016
Hypertension (yes) 2.83 (1.37–5.82) 0.005 1.63 (0.73–3.61) 0.184
Diabetes mellitus (yes) 1.88 (0.76–4.64) 0.169 1.51 (0.43–5.29) 0.522
Mechanical ventilation (days) 0.89 (0.84–0.94) < 0.001 0.78 (0.65–0.93) 0.006
 Mechanical ventilation*time 1.00 (1.002–1.006) < 0.001 1.01 (1.003–1.025) 0.007
  1. SHR sub-distribution hazard ratio, CI confidence interval, * interaction term