Subject | Sub group | No. studies | No. strains | Proportion (95% CI) | %Weight | P | I2 | P sig |
---|---|---|---|---|---|---|---|---|
Overall | VRSA | 62 | 12,816 | 0.06 (0.04, 0.09) | 100 | 0 | 0.9574 | 0 |
VRSA from MRSA | 25 | 3925 | 0.06 (0.03, 0.09) | 100 | 0 | 0.9366 | 0 | |
Quality | Â | Â | Â | Â | Â | Â | Â | Â |
High quality | VRSA | 43 | 10,990 | 0.05 (0.03, 0.07) | 70.83 | 0 | 0.9599 | 0 |
VRSA from MRSA | 19 | 3390 | 0.07 (0.03, 0.12) | 68.85 | 0 | 0.9531 | 0 | |
Low quality | VRSA | 19 | 1826 | 0.1 (0.04, 0.17) | 28.68 | 0 | 0.9460 | 0 |
VRSA from MRSA | 9 | 675 | 0.02 (0.01, 0.05) | 31.15 | 0.03 | 0.5328 | 0 | |
Continent | Â | Â | Â | Â | Â | Â | Â | Â |
Asia | VRSA | 46 | 11,074 | 0.05 (0.03, 0.08) | 75.03 | 0 | 0.9555 | 0 |
VRSA from MRSA | 22 | 3416 | 0.06 (0.03, 0.11) | 82.07 | 0 | 0.9443 | 0 | |
South America | VRSA | 2 | 171 | 0.03 (0.00, 0.17) | 1.39 | Â | Â | 0.16 |
VRSA from MRSA |  | – |  |  |  |  |  | |
Africa | VRSA | 7 | 720 | 0.16 (0.03, 0.35) | 11.20 | 0 | 0.9706 | 0 |
VRSA from MRSA | 1 | 50 | 0.00 (0.00, 0.07) | 3.06 | Â | Â | 0 | |
America | VRSA | 3 | 395 | 0.04 (0.02, 0.07) | 6.48 | 0.23 | 0.3054 | 0 |
VRSA from MRSA | 2 | 272 | 5(0.03, 0.08) | 8.08 | Â | Â | 1 | |
Europe | VRSA | 4 | 456 | 0.01 (0, 0.05) | 5.90 | 0.03 | 0.6616 | 0.14 |
VRSA from MRSA | 2 | 187 | 0 (0, 0.02) | 6.19 | Â | Â | 0.87 | |
Countries | Â | Â | Â | Â | Â | Â | Â | Â |
Pakistan | VRSA | 5 | 934 | 0.1 (0.01, 0.24) | 8.40 | 0 | 0.9693 | 0.01 |
VRSA from MRSA | 3 | 301 | 0.07 (0, 0.25) | 11.61 | Â | Â | 0.06 | |
India | VRSA | 14 | 5647 | 0.07 (0.03, 0.13) | 23.42 | 0 | 0.9778 | 0 |
VRSA from MRSA | 6 | 3529 | 0.06 (0, 0.18) | 23.50 | 0.01 | 0.98 | 0.03 | |
Brazil | VRSA | 3 | 203 | 0.03 (0.01, 0.07) | 4.48 | 0.00 | 0 | 0 |
VRSA from MRSA | 1 | 140 | 0.04 (0.01, 0.08) | 4.08 | Â | Â | 0 | |
Nigeria | VRSA | 2 | 273 | 0.29 (0.24, 0.35) | 3.30 | Â | Â | 0 |
VRSA from MRSA | – |  |  |  |  |  |  | |
Iran | VRSA | 16 | 3464 | 0.02 (0.01, 0.04) | 26.28 | 0 | 0.7848 | 0 |
VRSA from MRSA | 6 | 875 | 0.04(0.01, 0.08) | 23.20 | 0.01 | 67.03 | Â | |
Algeria | VRSA | 3 | 583 | 0.01 (0, 0.04) | 1.72 | Â | Â | 0.01 |
VRSA from MRSA | 1 | 220 | 0.02 (0, 0.05) | 4.08 | Â | Â | 0.01 | |
USA | VRSA | 2 | 363 | 0.04 (0.02, 0.07) | 3.39 | Â | Â | 0 |
VRSA from MRSA | 1 | 132 | 0.08 (0.04, 0.13) | 3.66 | Â | Â | 0 | |
Italy | VRSA | 3 | 448 | 0.02 (0, 0.05) | 5.03 | Â | Â | 0.02 |
VRSA from MRSA | 1 | 179 | 0.01 (0, 0.04) | 4.10 | Â | Â | 0.03 | |
Saudi Arabia | VRSA | 2 | 128 | 0.18 (0.12, 0.26) | 3.02 | Â | Â | 0 |
VRSA from MRSA | 1 | 98 | 0.15 (0.09, 0.24) | 3.95 | Â | Â | 0 | |
Tanzania | VRSA | 1 | 53 | 0.11 (0.04, 0.23) | 1.53 | Â | Â | 0 |
VRSA from MRSA | – | – | . (.,.) |  |  |  |  | |
Egypt | VRSA | 4 | 394 | 0.16 (0.01, 0.45) | 6.36 | 0 | 0.9719 | 0.02 |
VRSA from MRSA | 1 | 50 | 0 (0, 0.07) | 3.66 | Â | Â | 1 | |
Turkey | VRSA | 5 | 469 | 0.05 (0, 0.14) | 7.65 | 0 | 0.8895 | 0.02 |
VRSA from MRSA | 3 | 245 | 0.04 (0, 0.13) | 9.56 | Â | Â | 0.1 | |
Bangladesh | VRSA | 2 | 73 | 0.12 (0.05, 0.21) | 2.86 | Â | Â | 0 |
VRSA from MRSA | 2 | 73 | 0.27 (0.13, 0.43) | 5.76 | Â | Â | 0 | |
Germany | VRSA | 1 | 8 | 0.13 (0, 0.53) | 0.87 | Â | Â | 0.15 |
VRSA from MRSA | 1 | 8 | 0.13 (0, 0.53) | 2.09 | Â | Â | 0.15 | |
Jordan | VRSA | 1 | 139 | 0.04 (0.01, 0.08) | 1.68 | Â | Â | 0 |
VRSA from MRSA | – | – | . (.,.) |  |  |  |  | |
Isolate source | Â | Â | Â | Â | Â | Â | Â | Â |
Clinical | VRSA | 53 | 11,891 | 0.06 (0.04, 0.08) | 84.56 | 0 | 0.9582 | 0 |
VRSA from MRSA | 23 | 5779 | 0.06 (0.03, 0.10) | 85.92 | 0 | 0.9420 | 0 | |
Clinical, non-clinic | VRSA | 4 | 501 | 0.14 (0.00, 0.44) | 06.54 | 0 | 0.9815 | 0.04 |
VRSA from MRSA | 1 | 179 | 0.01 (0.00, 0.04) | 04.10 | Â | Â | 0.03 | |
Non-clinical | VRSA | 6 | 424 | 0.07 (0.01, 0.15) | 8.91 | 0 | 0.8615 | 0 |
VRSA from MRSA | 3 | 245 | 0.04 (0.00, 0.13) | 9.98 | Â | Â | 0.10 | |
AST method(s) | Â | Â | Â | Â | Â | Â | Â | Â |
MIC-base | VRSA | 25 | 5671 | 0.07 (0.04, 0.12) | 39.87 | 0 | 0.9599 | 0 |
VRSA from MRSA | 9 | 1223 | 0.09 (0.03, 0.17) | 30.99 | 0 | 0.874 | 0 | |
Mixed-methods | VRSA | 32 | 6596 | 0.04 (0.02, 0.07) | 51.95 | 0 | 0.9527 | 0 |
VRSA from MRSA | 17 | 4995 | 0.04 (0.01, 0.09) | 64.48 | 0 | 0.9538 | 0 | |
Disk diffusion | VRSA | 33 | 6736 | 0.12 (0.02, 0.27) | 8.18 | 0 | 0.9532 | 0 |
VRSA from MRSA | 1 | 85 | 0.05 (0.01, 0.17) | 3.52 | Â | Â | 0.03 |