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Table 6 Univariate and multivariate Cox regression analyses of variables associated with 30-day mortality of BSI in burn patients

From: Epidemiology and outcomes of bloodstream infections in severe burn patients: a six-year retrospective study

Variable Crude analysis Adjusted analysis
HR (95%CI) p value HR (95%CI) p value
Male 0.70 (0.20–2.47) 0.583   
Age 1.00 (0.97–1.04) 0.856   
Comorbidities 0.72 (0.21–2.53) 0.609   
Type of burn (Flame) 0.52 (0.17–1.60) 0.253   
 ≥ 80% TBSA 0.14 (0.05–0.44) 0.001 0.86 (0.22–3.38) 0.861
Accompanying third degree burns 22.7 (0.01,7204.37) 0.448   
Inhalation injury 1.55 (0.54–4.46) 0.417   
Mechanical ventilation 10.77 (1.42–81.54) 0.021 4.14 (0.41–41.53) 0.228
Coinfections before bacteremia
Skin infection 0.72 (0.25–2.08) 0.546   
Pneumonia 1.40 (0.53–3.72) 0.503   
CVC infection 0.36 (0.08–1.57) 0.171   
UTI 1.43 (0.19–10.84) 0.728   
AKI 42.85 (12.10–151.78)  < 0.001 12.26 (2.31–64.98) 0.003
Septic shock 36.98 (12.79–106.87)  < 0.001 4.36 (1.16–16.34) 0.031
Inappropriate empirical antimicrobial therapy 0.42 (0.15–1.16) 0.093 0.56 (0.17–1.89) 0.351
Inappropriate definitive antimicrobial therapy 0.25 (0.09–0.72) 0.010 0.52 (0.12–2.19) 0.371
  1. HR hazard ratio, CI confidence interval, TBSA total body surface area, CVC central venous catheter, UTI urinary tract infection, AKI acute kidney injury