|
Variable
|
Crude analysis
|
Adjusted analysis
|
|---|
|
HR (95%CI)
|
p value
|
HR (95%CI)
|
p value
|
|---|
|
Male
|
0.70 (0.20–2.47)
|
0.583
| | |
|
Age
|
1.00 (0.97–1.04)
|
0.856
| | |
|
Comorbidities
|
0.72 (0.21–2.53)
|
0.609
| | |
|
Type of burn (Flame)
|
0.52 (0.17–1.60)
|
0.253
| | |
|
≥ 80% TBSA
|
0.14 (0.05–0.44)
|
0.001
|
0.86 (0.22–3.38)
|
0.861
|
|
Accompanying third degree burns
|
22.7 (0.01,7204.37)
|
0.448
| | |
|
Inhalation injury
|
1.55 (0.54–4.46)
|
0.417
| | |
|
Mechanical ventilation
|
10.77 (1.42–81.54)
|
0.021
|
4.14 (0.41–41.53)
|
0.228
|
|
Coinfections before bacteremia
|
|
Skin infection
|
0.72 (0.25–2.08)
|
0.546
| | |
|
Pneumonia
|
1.40 (0.53–3.72)
|
0.503
| | |
|
CVC infection
|
0.36 (0.08–1.57)
|
0.171
| | |
|
UTI
|
1.43 (0.19–10.84)
|
0.728
| | |
|
AKI
|
42.85 (12.10–151.78)
|
< 0.001
|
12.26 (2.31–64.98)
|
0.003
|
|
Septic shock
|
36.98 (12.79–106.87)
|
< 0.001
|
4.36 (1.16–16.34)
|
0.031
|
|
Inappropriate empirical antimicrobial therapy
|
0.42 (0.15–1.16)
|
0.093
|
0.56 (0.17–1.89)
|
0.351
|
|
Inappropriate definitive antimicrobial therapy
|
0.25 (0.09–0.72)
|
0.010
|
0.52 (0.12–2.19)
|
0.371
|
- HR hazard ratio, CI confidence interval, TBSA total body surface area, CVC central venous catheter, UTI urinary tract infection, AKI acute kidney injury