Trends in prevalence of extended-spectrum beta-lactamase-producing Escherichia coli isolated from patients with community- and healthcare-associated bacteriuria: results from 2014 to 2020 in an urban safety-net healthcare system

Table 4 Annual percentage point changes in prevalence of antimicrobial resistant E. coli from bacteriuria episodes, 2014–2020

	Annual percent point change (95% CI)
	NIT	T/S	CIP	ESBL	Any AMR	MDR
Community onset	0.34 (0.16, 0.51)	0.64 (0.04, 1.23)	0.13 (− 0.37, 0.62)	0.91 (0.56, 1.26)	1.00 (0.40, 1.61)	0.25 (− 0.21, 0.72)
Healthcare onset/associated	1.61 (0.74, 2.47)	0.41 (− 1.07, 1.90)	− 0.59 (− 2.05, 0.87)	2.31 (1.01, 3.62)	− 0.18 (− 1.54, 1.18)	− 0.13 (− 1.52, 1.27)

Data from a public healthcare system; CI: confidence interval, NIT: nitrofurantoin, T/S: trimethoprim/sulfamethoxazole, CIP: ciprofloxacin, ESBL: extended-spectrum beta-lactamase, AMR: antimicrobial resistance, MDR: multidrug resistance. Logistic regression are univariate analyses including presence or absence of antimicrobial resistance to antibiotic and year from baseline

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