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Table 2 Meta-analysis results for resistance rate of each V. cholera serogroup in included studies

From: Global status of tetracycline resistance among clinical isolates of Vibrio cholerae: a systematic review and meta-analysis

Serogroup Number of studies Antibiotic Resistance rate (%)
(95% CI)
Heterogeneity test Begg’s test** p-value (two-tailed) Egger’s test*** p-value (two-tailed)
Min Max Pooled* (range) I2 (%) p-value a b
O1 44
16
TET
DOX
0
0
100
56
0.2 (0.1–0.3)
0.07 (0.03–0.1)
96.9
92.5
 < 0.001
 < 0.001
0.2
0.7
0.2
0.8
0.03
0.005
O139 2
1
TET
DOX
0
NA
2.5
NA
0.02 (0.01–0.04)
0.004 (0.0–0.06)
43
0.0
0.2
1.0
NA
NA
NA
NA
NA
NA
Non-O1, non-O139 8
3
TET
DOX
2.1
0.8
65.3
88.7
0.1 (0.05–0.3)
0.1 (0.001–0.9)
95.5
97.7
 < 0.001
 < 0.001
0.2
0.6
0.3
1.0
0.06
0.3
  1. TET tetracycline; DOX doxycycline; a: Kendall’s tau without continuity correction; b: Kendall’s tau with continuity correction; *Pooled resistance rate; **Begg and Mazumdar rank correlation; ***Egger’s regression intercept; NA: not applicable