Table 3 Profiling of genetic mutations and MICs for BDQ-resistant MTB isolates
Locus | Mutation | No. of isolates with corresponding MIC (μg/ml) | Total (%) | ||
|---|---|---|---|---|---|
0.25 | 0.5 | 1 | |||
Rv0678 | Ala86Val | 1 | 1 (10.0) | ||
Ile108Thr | 1 | 1 (10.0) | |||
Arg109Pro | 1 | 1 (10.0) | |||
Deletion A in codon 110 | 1 | 1 (10.0) | |||
Wild-type | 4 | 1 | 1 | 6 (60.0) | |
Total | 5 | 4 | 1 | 10 (100.0) | |