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Table 3 S. aureus and E. faecium susceptibility patterns for selected antibiotics per year

From: The epidemiology of bloodstream infections and antimicrobial susceptibility patterns in Thuringia, Germany: a five-year prospective, state-wide surveillance study (AlertsNet)

  2015 2016 2017 2018 2019 OR (95% CI)
p value
S. aureus
Oxacillin/Methicillin 608/63
(10.4)
772/48
(6.2)
818/33
(4.0)
933/50
(5.4)
824/21
(2.5)
0.74 (0.66; 0.83) < 0.001
Rifampicin 550/2
(0.4)
598/4
(0.7)
510/10
(1.9)
735/2
(0.3)
597/5
(0.8)
1.05 (0.81; 1.37) 0.71
Fluoroquinolones 608/190
(31.3)
767/186
(24.3)
813/167
(20.5)
800/144
(18.0)
627/126
(20.1)
0.81 (0.76; 0.87) < 0.001
E. faecium
Vancomycin 227/38
(16.7)
227/68
(30.0)
215/68
(31.6)
228/97
(42.5)
186/50
(26.9)
1.19 (1.08; 1.31) < 0.001
Teicoplanin 186/32
(17.2)
184/49
(26.6)
150/42
(28.0)
196/56
(28.6)
156/22
(14.1)
0.99 (0.88; 1.12) 0.92
Linezolid 220/3
(1.4)
219/2
(0.9)
205/4
(2.0)
222/20
(9.0)
185/5
(2.7)
1.50 (1.19; 1.90) < 0.001
Daptomycin 7/1
(14.3)
16/2
(12.5)
24/2
(8.3)
32/3
(9.4)
48/8
(16.7)
1.08 (0.74; 1.57) 0.71
Tigecycline 149/1
(0.7)
159/1
(0.6)
190/2
(1.1)
213/1
(0.5)
161/6
(3.7)
1.79 (0.89; 3.62) 0.10
  1. Number of tested isolates/number of resistant isolates (% resistant). The right column displays the results from the logistic regression with GEE as odds ratio (OR) for resistance for the unadjusted linear predictor year (i.e. OR per year) with 95% confidence interval (95% CI) and corresponding two-sided p value