Table 4 Susceptibility patterns for selected antibiotic substances and pathogens per year

Escherichia coli

Aminopenicillin

941/486

(51.6)

1,282/711

(55.5)

1,426/785

(55.0)

1,595/920

(57.7)

1,536/940

(61.2)

1.06 (1.02; 1.10) 0.006

Fluoroquinolones

941/221

(23.5)

1,286/315

(24.5)

1,441/367

(25.5)

1,600/438

(27.4)

1,567/384

(24.5)

1.01 (0.97; 1.05) 0.72

Cefotaxime

938/100

(10.7)

973/134

(13.8)

912/122

(13.4)

1,228/178

(14.5)

1,355/197

(14.5)

1.08 (1.02; 1.14). 0.007

Carbapenems

941/1

(0.1)

1,286/3

(0.2)

1,441/3

(0.2)

1,600/0

(0.0)

1,538/1

(0.1)

–⁶

Aminoglycosides

941/57

(6.1)

1,286/122

(9.5)

1,473/143

(9.7)

1,594/151

(9.5)

1,535/280

(18.2)²

1.30 (1.21; 1.40) < 0.001

Fosfomycin

339/1

(0.4)

562/6

(1.1)

630/6

(1.0)

637/9

(1.4)

518/7

(1.4)

–⁶

Trimethoprim-sulfamethoxazole

941/293

(31.1)

1281/408

(31.9)

1435/439

(30.6)

1593/444

(27.9)

1533 /403

(26.3)

0.93 (0.89; 0.97) < 0.001

Klebsiella pneumoniae

Fluoroquinolones

181/25

(13.8)

232/38

(16.4)

227/40

(17.6)

254/49

(19.3)

270/36

(13.3)

1.02 (0.91; 1.15) 0.72

Cefotaxime

181/18

(9.9)

197/26

(13.3)

154/21

(13.6)

202/24

(11.9)

242/18

(7.4)

0.93 (0.81; 1.08) 0.35

Carbapenems

181/2

(1.1)

232/0

(0.0)

227/0

(0.0)

254/2

(0.8)

270/2

(0.7)

–⁶

Aminoglycosides

181/7

(3.9)

232/12

(5.2)

227/14

(6.2)

253/18

(7.1)

270/33

(12.2)²

1.47 (1.19; 1.82) < 0.001

Fosfomycin

54/6

(11.1)

117/19

(16.2)

113/15

(13.3)

115/16

(13.9)

92/12

(13.0)

1.01 (0.82; 1.24) 0.95

Trimethoprim-sulfamethoxazole

181/22

(12.2)

231/34

(14.7)

227/33

(14.5)

253/33

(13.0)

270/39

(14.4)

1.06 (0.88; 1.26) 0.56

Pseudomonas aeruginosa

Fluoroquinolones

48/10

(16.3)

72/15

(18.1)

87/23

(16.5)

120/19

(13.5)

–⁵

1.21 (0.97; 1.51) 0.09

Ceftazidime

47/3

(4.8)

72/3

(2.8)

85/7

(7.2)

127/6

(4.0)

–⁵

2.14 (1.29; 3.54) 0.003

Piperacillin/Tazobactam

46/7

(12.2)

71/4

(5.6)

85/9

(9.5)

131/19

(14.1)

–⁵

1.30 (0.97; 1.74) 0.07

Carbapenems

46/4

(9.8)

72/10

(13.9)

88/17

(17.4)

131/17

(11.7)

–⁵

1.17 (0.92; 1.49) 0.20

Aminoglycosides

47/6

(11.9)

72/4

(2.8)

88/8

(7.0)

129/3

(1.6)

–⁵

1.03 (0.72; 1.47) 0.88

Combined resistance³

46/5

(10.9)

71/3

(4.2)

87/8

(9.2)

127/7

(5.5)

–⁵

–⁶

Acinetobacter spp.

–⁵

Fluoroquinolones

27/5

(18.5)

33/6

(18.2)

35/11

(31.4)

32/8

(25.0)

–⁵

–⁶

Carbapenems

27/0

(0.0)

33/1

(3.0)

35/3

(8.6)

33/1

(3.0)

–⁵

–⁶

Aminoglycosides

27/1

(3.7)

33/0

(0.0)

33/3

(9.1)

32/1

(3.1)

–⁵

–⁶

Combined resistance⁴

27/0

(0.0)

33/0

(0.0)

33/2

(6.1)

32/1

(3.1)

–⁵

–⁶