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Table 5 Drug-resistance genes and plasmids identified in bacteria isolated from commercial herbal medicines in Africa from 2000 to 2021

From: Antibiotic-resistance in medically important bacteria isolated from commercial herbal medicines in Africa from 2000 to 2021: a systematic review and meta-analysis

Isolates screened (N)

MDR Phenotypes/genotypes

Isolates with MDR phenotypes/genotypes

N, (%)

Species

(a) Multi-drug resistance phenotypes and/or genotypes

06

ESBL

1, (17.0%)

K. pneumoniae

98

ESBL

13, (13.3%)

Salmonella spp.

13

ESBL

4, (30.8%)

E. coli

13

ESBL

4, (30.8%)

P. vulgaris

13

ESBL

3, (23.1%)

K. pneumoniae

96

blaCTX-M -ESBL

33, (34.4%)

P. penneri, K. pneumoniae, C. diversus, E. cloacae, M. morganii

blaCMY-ESBL

31, (32.3%)

E. cloacae, E. aerogenes, K. pneumoniae

Σ = 239

 

Σ = 89 (37.2%)

 

Isolates tested (N)

Resistance plasmids detected

Isolates with drug resistance plasmids

Number

MW(Kb)

N, (%)

Species

(b) Resistance plasmids

16

1

9416

1 (6.3%)

Salmonella spp.

11

2

23,130

2 (18.2%)

P. vulgaris

1

2322

1 (9.1%)

1

9416

1 (9.1%)

1

2322

1 (9.1%)

47

0

Nil

0 (0.0%)

Escherichia coli

29

0

Nil

0 (0.0%)

Klebsiella pneumoniae

Σ = 103

Σ = 06

 

Σ = 06 (5.8%)

 
  1. ESBL = Extended Spectrum β-lactamase enzymes, MW = Molecular Weight, Kb = kilobases