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Table 4 Significant predictors associated with genetic response after FMT

From: Faecal microbiota transplantation reduces amounts of antibiotic resistance genes in patients with multidrug-resistant organisms

 

Univariate analysis

Unadjusted hazard ratio

95% CI

p-value

Age

1.008

0.92–1.024

0.597

Sex

0.499

0.190–1.307

0.149

MDRO carriage

   

 VRE

1.000

Reference

0.261

 CPE

0.417

0.46–1.188

0.102

 VRE/CPE

0.630

0.182–2.179

0.465

Antibiotic resistance gene

   

 VanA

1.000

Reference

0.773

 blaKPC

0.620

0.078–4.947

0.652

 blaOXA

0.831

0.099–6.959

0.864

Duration of carriage before FMT

0.999

0.994–1.004

0.670

Antibiotics used before FMT within 1 week

0.609

0.249–1.489

0.277

Antibiotics used after FMT within 1 week

1.312

0.472–3.651

0.603

  1. FMT, faecal microbiota transplantation; MDRO, multidrug-resistant organism; VRE, vancomycin-resistant enterococci; CPE, carbapenemase-producing Enterobacteriaceae