Skip to main content

Table 3 Multivariate logistic regression analysis for prognostic factors of nosocomial infections in cancer patients in the training cohort

From: Establishment and validation of a nomogram to predict the in-hospital death risk of nosocomial infections in cancer patients

Variables β SE Wald OR (95% CI) P
ECOG-PS
 0–2      
 3–4 1.49 0.40 14.02 4.46 (2.04–9.74) < 0.001*
Underlying malignancy type
 Head and neck cancer 0.85 0.56 2.30 2.33 (0.78–6.98) 0.130
 Lung cancer 0.26 0.33 0.62 1.30 (0.68–2.48) 0.431
 Gynecological cancer − 0.60 0.43 1.94 0.55 (0.24–1.28) 0.164
Stage of cancer − 0.03 0.29 0.01 0.97 (0.55–1.71) 0.924
Source of infection      
 Gastrointestinal tract 0.13 0.58 0.05 1.14 (0.36–3.59) 0.819
 Urinary tract − 0.54 0.42 1.63 0.59 (0.26–1.33) 0.202
 Skin and soft tissue − 1.25 0.79 2.50 0.29 (0.06–1.35) 0.114
 BSI − 0.66 0.46 2.06 0.52 (0.21–1.27) 0.152
Comorbidities
 COPD 0.14 0.54 0.06 1.15 (0.40–3.32) 0.803
 Liver disease 0.80 0.44 3.39 2.23 (0.95–5.22) 0.066
 Renal disease 0.86 0.50 2.95 2.36 (0.89–6.26) 0.086
Existence of fever 0.27 0.32 0.70 1.31 (0.70–2.45) 0.405
Previous surgery (within 1 month)      0.006*
 None    10.21   
 Curative surgery − 1.69 0.53 10.20 0.18 (0.07–0.52) 0.001*
 Palliative surgery − 0.46 0.77 0.36 0.63 (0.14–2.87) 0.550
Empirical antibiotic treatment (within 1 month)
 Combination therapy 0.36 0.32 1.28 1.43 (0.77–2.67) 0.258
Length of antimicrobial therapy < 7 days 0.93 0.30 9.39 2.54 (1.40–4.60) 0.002*
Presence of indwelling catheters − 0.16 0.29 0.31 0.85 (0.48–1.51) 0.576
Mechanical ventilation 1.43 0.55 6.78 4.17 (1.42–12.23) 0.009*
Septic shock 1.15 0.43 7.30 3.16 (1.37–7.30) 0.007*
Laboratory examination results
 Platelet count < 100.0 × 109/L 0.19 0.34 0.31 1.21 (0.62–2.36) 0.578
 Lymphocytes count < 1.0 × 109/L 0.33 0.29 1.30 1.40 (0.79–2.48) 0.255
 Albumin < 30.0 g/L 0.85 0.29 8.84 2.34 (1.34–4.10) 0.003*
Fungi
 Candida albicans 0.22 0.43 0.25 1.24 (0.53–2.90) 0.617
 Aspergillus flavus 0.64 0.69 0.85 1.89 (0.49–7.32) 0.355
  1. SE, standardized error; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status; BSI, bloodstream infection; COPD, chronic obstructive pulmonary disease
  2. *Indicates statistical significance