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Table 3 Multivariate logistic regression analysis for prognostic factors of nosocomial infections in cancer patients in the training cohort

From: Establishment and validation of a nomogram to predict the in-hospital death risk of nosocomial infections in cancer patients

Variables

β

SE

Wald

OR (95% CI)

P

ECOG-PS

 0–2

     

 3–4

1.49

0.40

14.02

4.46 (2.04–9.74)

< 0.001*

Underlying malignancy type

 Head and neck cancer

0.85

0.56

2.30

2.33 (0.78–6.98)

0.130

 Lung cancer

0.26

0.33

0.62

1.30 (0.68–2.48)

0.431

 Gynecological cancer

− 0.60

0.43

1.94

0.55 (0.24–1.28)

0.164

Stage of cancer

− 0.03

0.29

0.01

0.97 (0.55–1.71)

0.924

Source of infection

     

 Gastrointestinal tract

0.13

0.58

0.05

1.14 (0.36–3.59)

0.819

 Urinary tract

− 0.54

0.42

1.63

0.59 (0.26–1.33)

0.202

 Skin and soft tissue

− 1.25

0.79

2.50

0.29 (0.06–1.35)

0.114

 BSI

− 0.66

0.46

2.06

0.52 (0.21–1.27)

0.152

Comorbidities

 COPD

0.14

0.54

0.06

1.15 (0.40–3.32)

0.803

 Liver disease

0.80

0.44

3.39

2.23 (0.95–5.22)

0.066

 Renal disease

0.86

0.50

2.95

2.36 (0.89–6.26)

0.086

Existence of fever

0.27

0.32

0.70

1.31 (0.70–2.45)

0.405

Previous surgery (within 1 month)

    

0.006*

 None

  

10.21

  

 Curative surgery

− 1.69

0.53

10.20

0.18 (0.07–0.52)

0.001*

 Palliative surgery

− 0.46

0.77

0.36

0.63 (0.14–2.87)

0.550

Empirical antibiotic treatment (within 1 month)

 Combination therapy

0.36

0.32

1.28

1.43 (0.77–2.67)

0.258

Length of antimicrobial therapy < 7 days

0.93

0.30

9.39

2.54 (1.40–4.60)

0.002*

Presence of indwelling catheters

− 0.16

0.29

0.31

0.85 (0.48–1.51)

0.576

Mechanical ventilation

1.43

0.55

6.78

4.17 (1.42–12.23)

0.009*

Septic shock

1.15

0.43

7.30

3.16 (1.37–7.30)

0.007*

Laboratory examination results

 Platelet count < 100.0 × 109/L

0.19

0.34

0.31

1.21 (0.62–2.36)

0.578

 Lymphocytes count < 1.0 × 109/L

0.33

0.29

1.30

1.40 (0.79–2.48)

0.255

 Albumin < 30.0 g/L

0.85

0.29

8.84

2.34 (1.34–4.10)

0.003*

Fungi

 Candida albicans

0.22

0.43

0.25

1.24 (0.53–2.90)

0.617

 Aspergillus flavus

0.64

0.69

0.85

1.89 (0.49–7.32)

0.355

  1. SE, standardized error; OR, odds ratio; ECOG-PS, Eastern Cooperative Oncology Group Performance Status; BSI, bloodstream infection; COPD, chronic obstructive pulmonary disease
  2. *Indicates statistical significance
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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