Table 1 Characteristics of the 32 E. cloacae complex isolates from the study period, ordered by WGS clusters and patient numbers

ID01

10,457

Sep-17

NICU

perianal

E. hormaechei subsp. steigerwaltii

CTX-R, ERT-I

bla_ACT-15, fosA

1

1

A

50

A

ID01

10,502

Sep-17

NICU

oropharyngeal

E. hormaechei subsp. steigerwaltii

bla_ACT-15, fosA

1

1

A

50

A

ID02 (1)

10,501

Sep-17

NICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

bla_ACT-15, fosA

1

1

A

50

A

ID03

10,500

Sep-17

NICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

GEN-R

bla_ACT-15, fosA

1

1

A

50

A

ID03

10,504

Sep-17

NICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

CTX-R

bla_ACT-15, fosA

1

1

n.d

50

A

ID05

10,505

Sep-17

NICU

perianal

E. hormaechei subsp. steigerwaltii

CTX-R, ERT-I, GEN-R

bla_ACT-15, fosA

1

1

n.d

50

B

ID05

10,481

Sep-17

NICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

CTX-R, ERT-R

bla_ACT-15, fosA

1

1

A

50

A

ID06 (1)

10,503

Sep-17

NICU

oropharyngeal

E. hormaechei subsp. steigerwaltii

GEN-R

bla_ACT-15, fosA

1

1

A

50

A

ID06 (1)

10,668

Oct-17

PICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

CTX-R

bla_ACT-15, fosA

1

1

n.d

50

A

ID07

10,593

Oct-17

PICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

GEN-R

bla_ACT-15, fosA

1

1

A

50

A

ID07

10,721

Oct-17

PICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

bla_ACT-15, fosA

1

1

n.d

50

A

ID15

10,832

Nov-17

PICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

CTX-R, ERT-R

bla_ACT-15, fosA

1

1

A

50

A

ID16

10,833

Nov-17

PICU

nasal/oropharyngeal

E. hormaechei subsp. steigerwaltii

bla_ACT-15, fosA

1

1

A

50

A

ID04

10,506

Sep-17

PICU

central line

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID08

10,539

Oct-17

NICU

tracheal secretions

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID10

10,720

Oct-17

NICU

oropharyngeal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID12

10,722

Nov-17

NICU

perianal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID14

10,834

Nov-17

NICU

oropharyngeal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID17

10,886

Dec-17

NICU

perianal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

B

168

A

ID18 (2)

10,909

Dec-17

PICU

perianal

E. hormaechei subsp. hoffmannii

CTX-R

bla_ACT-14, fosA

2

2

B

168

A

ID19 (2)

10,940

Dec-17

NW

perianal

E. hormaechei subsp. hoffmannii

CTX-R, ERT-R

bla_ACT-14, fosA

2

2

B

168

A

ID21 (3)

10,995

Dec-17

NICU

perianal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

2

2

n.d

168

A

ID22 (3)

10,994

Jan-18

NICU

oropharyngeal

E. hormaechei subsp. hoffmannii

CTX-R

bla_ACT-14, fosA

2

2

B

168

A

ID13

10,749

Nov-17

PICU

tracheal secretions

E. hormaechei subsp. oharae

bla_ACT-7

3

3

C

1086

H

ID13

11,155

Feb-18

PICU

tracheal secretions

E. hormaechei subsp. oharae

CTX-R, ERT-R, IPM-I, MEM-R

bla_ACT-7

3

3

C

1086

E

ID20

10,938

Dec-17

PICU

perianal

E. hormaechei subsp. steigerwaltii

CTX-R

bla_ACT-7, fosA

4

4

D

116

C

ID24

11,062

Jan-18

PICU

eye

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

5

5

E

104

D

ID24

11,115

Jan-18

PICU

perianal

E. hormaechei subsp. hoffmannii

CTX-R

bla_ACT-14, fosA

5

5

E

104

D

ID26

11,183

Feb-18

NICU

perianal

E. cloacae subsp. cloacae

bla_CMH-3, fosA

6

6

F

477

F

ID27 (4)

11,227

Feb-18

PICU

nasal/oropharyngeal

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

7

7

G

278

G

ID27 (4)

12,015

Aug-18

PICU

groin

E. hormaechei subsp. hoffmannii

CTX-R, CIP-I, MXF-R

bla_ACT-14, fosA

7

7

G

278

B

ID29 (4)

11,229

Feb-18

PICU

eye

E. hormaechei subsp. hoffmannii

bla_ACT-14, fosA

7

7

G

278

G