Fig. 1

Categorization of automated and gradient strip test results for carbapenem susceptibility in E. coli and K. pneumoniae between 2017 and 2019 in 43 laboratories participating in the Infectious Diseases Surveillance Information System for Antimicrobial Resistance (ISIS-AR) in the Netherlands. EC: Escherichia coli, KP: Klebsiella pneumoniae. Screening breakpoint: meropenem 0.25 mg/L, imipenem 1 mg/L (according to the Dutch Society for Medical Microbiology (NVMM) Guideline Laboratory detection of highly resistant microorganisms (HRMO) (version 2.0, 2012) [11]). Clinical S breakpoint: meropenem 2 mg/L, imipenem 2 mg/L (according to EUCAST clinical breakpoint table, version 9.0 [12]). Clinical R breakpoint: meropenem 8 mg/L, imipenem 4 mg/L (according to EUCAST clinical breakpoint table, version 9.0 [12])