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Table 4 Most frequently identified carbapenemase-encoding alleles and the corresponding reported geographic regions of the world and countries for persons who were recently hospitalized abroad, January 2017–June 2019a, the Netherlands

From: Epidemiology of carbapenem-resistant and carbapenemase-producing Enterobacterales in the Netherlands 2017–2019

Carbapenemase-encoding allele (WGS)

Number of persons being hospitalized abroad for > 24 h during the previous two monthsb (n)

Geographic region(s) most frequently reported (n)

Most prevalent countries

(n)

blaOXA-48

84

Northern Africa (35)

Morocco (29)

Western Asia (30)

Turkey (29)

Southern Europe (6)

Egypt (4)

Spain (4)

blaNDM-1

37

Southern Europe (9)

Greece (5)

South-eastern Asia (6)

Turkey (4)

Northern Africa (5)

India (3)

Western Asia (5)

Thailand (3)

South Asia (5)

 

blaNDM-5

29

Southern Asia (12)

India (10)

Northern Africa (10)

Egypt (7)

Morocco (3)

blaOXA-181

22

South Asia (11)

India (7)

South-eastern Asia (4)

Turkey (4)

Western Asia (4)

Thailand (3)

blaKPC-2

15

Southern Europe (8)

Greece (6)

Western Asia (4)

Turkey (3)

blaOXA-244

13

Western Asia (6)

Turkey (6)

Northern Africa (4)

Egypt (3)

blaKPC-3

12

Southern Europe (11)

Italy (8)

Portugal (3)

blaVIM-1

11

Southern Europe (9)

Spain (5)

  1. CPE carbapenemase-producing Enterobacterales; WGS whole genome sequencing
  2. aOnly data from the pathogen surveillance (Type-Ned CPE) for persons with epidemiological data available were used in this table (sampling date January 2017–June 2019). Recent hospitalization abroad was defined as hospitalized abroad for more than 24 h during the two months prior to the CPE positive culture
  3. bPersons with multiple identified carbapenemase-encoding alleles in a single sample were included in these numbers