Table 1 Mutations identified conferring resistance to the different anti-TB drugs
Drug | Resistance profile | Gene mutation |
|---|---|---|
Rifampicin | Resistant | rpoB p.Ser450Leu |
Isoniazid | Resistant | katG p.Ser315Thr |
Fluroquinolones | Resistant | gyrA p.Asp94Gly |
Ethionamide | Resistant | ethA c.477del |
Bedaquiline | Resistant | Rv0678 p.Glu49fs |
Clofazimine | Resistant | Rv0678 p.Glu49fs |
Linezolid | Resistant | rplC p.Cys154Arg |