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Table 1 Demographics of the study population

From: Impact of early antibiotic exposure on the risk of colonization with potential pathogens in very preterm infants: a retrospective cohort analysis

 

GA < 32 weeks

(n = 1407, 100%)

GA < 28 weeks*

(n = 480, 34.1%)

Gestational age (weeks)

28.8 ± 2.4

26.0 ± 1.4

Birth weight (g)

1150.3 ± 415.9

754.0 ± 209.8

Gender male (%)

720 (51.2)

237 (49.4)

Multiple pregnancies (%)

567 (40.3)

182 (37.9)

Admitting hospital

  

 I

627 (44.6)

222 (46.3)

 II

314 (22.3)

91 (19.0)

 III

466 (33.1)

167 (34.8)

Prenatal ABX (%)

510 (47.0; n = 1085)

221 (47.7; n = 463)

Antenatal steroids (%)

1245 (88.5; n = 1380)

424 (88.3; n = 473)

pPROM (%)

382 (31.7; n = 1204)

129 (31.3; n = 421)

Birth mode (%)

  

 Spontaneous

152 (10.8)

57 (11.9)

 Elective C/S

711 (54.8)

241 (50.2)

 Emergency C/S

482 (34.3)

182 (37.9)

APGAR 10

8.9 ± 1.0

8.6 ± 1.2

SGA (%)

214 (15.2; n = 1406)

90 (18.8; n = 479)

Mechanical ventilation (%)

474 (33.7)

303 (63.1)

Early ABX (%)

911 (64.7)

428 (89.2)

EOS (%)

38 (2.7)

24 (5.0)

FIP (%)

56 (4.0; n = 1403)

45 (9.4; n = 479)

NEC (%)

41 (2.9; n = 1406)

30 (6.3)

LOS (%)

139 (9.9)

98 (20.4)

BPD (%)

114 (8.1)

86 (17.9)

ROP (%)

228 (16.2; n = 1170)

177 (38.3; n = 462)

Death (%)

14 (1.0)

8 (1.7)

  1. GA gestational age; pPROM premature preterm rupture of membranes; C/S caesarean section; SGA small for gestational age; ABX antibiotics; EOS early onset sepsis; FIP focal intestinal perforation; NEC necrotizing enterocolitis; LOS late onset sepsis; BPD bronchopulmonary dysplasia; ROP retinopathy of prematurity
  2. *Subgroup analysis