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Table 1 Characteristics of study population by antibiotic-not-susceptible uUTI versus antibiotic-susceptible uUTI during first-line therapy prescribed

From: Economic burden of antibiotic-not-susceptible isolates in uncomplicated urinary tract infection: Analysis of a US integrated delivery network database

Variable

Unmatched (n = 2565)

Matched (n = 2018)

 

Susceptible (n = 1535)

Not-susceptible (n = 1030)

Std. mean difference

Susceptible (n = 1009)

Not-susceptible (n = 1009)

Std. mean difference

Demographic characteristics

Mean age, years

42.83

44.42

0.081

43.95

44.12

0.008

Race, mean proportion of patients

White

0.611

0.582

0.060

0.586

0.584

0.004

African American

0.243

0.273

0.068

0.259

0.268

0.020

Asian

0.033

0.034

0.004

0.035

0.035

0

Other race

0.059

0.057

0.006

0.063

0.058

0.021

Unknown race/none/declined to answer

0.054

0.054

0.001

0.057

0.056

0.009

Ethnicity, mean proportion of patients

Hispanic

0.030

0.030

0.001

0.030

0.031

0.006

Non-Hispanic

0.872

0.876

0.012

0.879

0.873

0.018

Other ethnicity

0.002

0.007

0.073

0.001

0.007

0.095

Unknown (none/declined to answer)

0.096

0.087

0.031

0.090

0.089

0.003

Health insurance, mean proportion of patients

Private insurance

0.632

0.585

0.095

0.589

0.595

0.012

Medicare/Medicaid

0.143

0.177

0.091

0.160

0.170

0.029

Other insurance

0.225

0.238

0.031

0.252

0.235

0.039

Charlson comorbidities, mean numbers

Charlson Comorbidity Score

0.053

0.064

0.032

0.053

0.054

0.003

Hemiparesis

0.001

0

0.036

0

0

0

Renal disease

0.001

0

0.036

0

0

0

Myocardial infarction

0

0.001

0.044

0

0.001

0.045

COPD

0.021

0.022

0.006

0.021

0.019

0.014

Rheumatic disease

0.005

0.007

0.021

0.006

0.007

0.012

Peptic ulcer

0.001

0

0.036

0.001

0

0.045

Mild liver disease

0.003

0.004

0.022

0.001

0.004

0.060

Moderate/severe liver disease

0

0.001

0.044

0

0.001

0.045

Dementia

0.006

0.009

0.034

0.008

0.005

0.037

Peripheral vascular disorder

0.003

0.004

0.022

0.003

0.004

0.017

Cerebrovascular disease

0.005

0.003

0.027

0.004

0.003

0.017

Congestive heart failure

0.003

0.001

0.039

0.002

0.001

0.026

Healthcare resource use (180 days pre-index), mean number of events per patient in the 180 days pre-index

Inpatient encounters (all cause)

0.004

0.012

0.077

0.001

0.003

0.045

Outpatient encounters (all cause)

1.024

1.066

0.022

1.014

0.995

0.011

Outpatient clinic encounters (all cause)

0.897

0.975

0.046

0.929

0.912

0.011

Outpatient ambulatory surgery encounters (all cause)

0.01

0.014

0.026

0.012

0.009

0.028

Outpatient other encounters (all cause)

0.117

0.078

0.087

0.073

0.074

0.003

ED encounters (all cause)

0.052

0.084

0.103

0.065

0.066

0.003

Drug orders (all cause)

1.742

2.129

0.068

1.847

1.778

0.016

Any antibiotic use

0.098

0.150

0.158

0.097

0.147

0.152

  1. COPD chronic obstructive pulmonary disease; ED emergency department; Std. standard; uUTI uncomplicated urinary tract infection