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Table 1 Molecular characterization of S. aureus strains with reduced vancomycin susceptibility from 2006–2019

From: Impact of vancomycin use trend change due to the availability of alternative antibiotics on the prevalence of Staphylococcus aureus with reduced vancomycin susceptibility: a 14-year retrospective study

Strain ID Year VISA/hVISA MLST SCCmec type spa type agr PFGE pulsotype Mutation sites found
vraR vraS graR graS walR walK rpoB
K01-SAU-06-1583 2006 hVISA ST72 IVA t324 I P10 E59D T224I
K01-SAU-06-1590 2006 hVISA ST5 II t002 II P1 A113V
K01-SAU-06-1591 2006 hVISA ST5 II t002 II P4
K01-SAU-06-1613 2006 hVISA ST5 II t002 II P1 A113V
K01-SAU-07-1192 2007 hVISA ST5 II t2460 II P1 A113V
K01-SAU-07-1193 2007 hVISA ST239 III t037 I P7 E59D D148Q L26F, I59L, T224I A468T
K01-SAU-07-1208 2007 hVISA ST5 II t2460 II P1 A113V
K01-SAU-07-1209 2007 hVISA ST5 II t2460 II P3 E99K, E117G
K01-SAU-07-1211 2007 hVISA ST5 II t2460 II P2 E87A, A113V
K01-SAU-09-9664 2009 VISA ST5 II t2460 II P11
K01-SAU-10-447 2010 hVISA ST72 IVA t148 NT P8 E59D   
K01-SAU-10-476 2010 hVISA ST5 II t2460 II P11
K01-SAU-11-095 2011 hVISA ST5 II t2460 II P11
K01-SAU-11-298 2011 VISA ST72 IVA t324 I P8 E59D, E127K T224I H481Y
K01-SAU-14-050 2014 hVISA ST5 II t2460 II P11
K01-SAU-15-061 2015 hVISA ST5 II t2460 II P11 T518S*
K01-SAU-16-107 2016 hVISA ST72 IVA t664 I P9
K01-SAU-16-135 2016 hVISA ST5 II t2460 II P11 A477D
K01-SAU-17-044 2017 hVISA ST5 II t2460 II P6        A477D
K01-SAU-17-072 2017 hVISA ST5 II t9353 II P6        
K01-SAU-17-144 2017 hVISA ST5 II t9353 II P6        
K01-SAU-18-012 2018 hVISA ST5 II t2460 II P7        P475S
K01-SAU-18-025 2018 hVISA ST5 II t2460 II P7        A477D
K01-SAU-18-066 2018 hVISA ST5 II t2460 II P3        
K01-SAU-19-184 2019 hVISA ST5 II t2460 II P5       A400V