Table 5 Patient outcomes according to the empirical antimicrobial treatment strategy used

Emergence of new MDR pathogens^a

23 (9.1%)

19 (11.9%)

4 (4.2%)

Clinical cure on day 7

135 (53.1%)

88 (55.3%)

47 (49.5%)

ICU mortality^a

18 (7.1%)

14 (8.8%)

4 (4.2%)

28-day mortality (n = 253)

31 (12.3%)

23 (14.6%)

8 (8.4%)

Number of days in the ICU (N = 236)^{a, b}

7 (4–15)

7 (4–15)

7 (3–16)

On vasoactive drugs

2 (0–5)

3 (1–6)

1 (0–5)

On Invasive mechanical ventilation

3 (0–8)

4 (0–9)

2 (0–5)

Receiving renal replacement therapy

0 (0–0)

0 (0–0)

0 (0–0)

ICU-free days (N = 221)^{a, c}

21 (11–24)

21 (10–24)

21 (11–25)

Hospital-free days (N = 221)^{a, c}

0 (0–9)

0 (0–3)

0 (0–15)

Antimicrobial-free days (N = 221)^{a, c}

14 (5–20)

13 (3–18)

17 (8–21)

Infection relapse^a

14 (5.6%)

7 (4.5%)

7 (7.4%)