Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Table 2 The effect of season and temperature on the incidence of E. coli bloodstream infection, by place of onset

Variable	Community onset			Hospital onset
Variable	IRR	95% CI	P	IRR	95% CI	P
Holiday season	1.07	0.97, 1.18	0.2	1.03	0.88, 1.19	0.7
Temperature, °C*	1.01	1.00, 1.02	0.008	1.00	0.99, 1.02	0.6
Female sex	1.42	1.33, 1.52	< 0.001	0.98	0.88, 1.08	0.7
Age category, years
18–44	–	–		–	–
45–64	2.18	1.94, 2.44	< 0.001	1.93	1.62, 2.32	< 0.001
65–74	2.97	2.65, 3.32	< 0.001	2.26	1.90, 2.70	< 0.001
75 +	7.84	7.05, 8.72	< 0.001	3.25	2.75, 3.85	< 0.001
Number of months since January 2018	1.01	1.00, 1.01	0.02	1.01	1.00, 1.02	0.01

*When temperature was modelled dichotomously as ≤ 25 °Cor > 25 °C, results were IRR 1.16 (95% CI 1.05, 1.27) p = 0.002 for CO BSI and 1.03 (95% CI 0.89, 1.19) p = 0.7 for HO BSI
Holiday season: July to October
IRR Incidence rate ratio, CI confidence interval

ISSN: 2047-2994