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Table 1 Minimum inhibitory concentrations (MICs) for the three Klebsiella quasipneumoniae strains R55 (March), R58 (April), and R73 (May) isolated from wastewater samples. EUCAST epidemiological cut-offs for K. pneumoniae (ECOFFs, www.eucast.org, accessed on 3 November 2022) relative to the tested antimicrobials are reported

From: Wastewater-based surveillance in Italy leading to the first detection of mcr-10-positive Klebsiella quasipneumoniae

Antimicrobial

MIC values (mg/L)

ECOFF (R > mg/L)

R55

R58

R73

Colistin (COL)

 ≤ 0.12

 ≤ 0.12

 ≤ 0.12

2

Cefepime (FEP)

2

0.12

0.5

0.125

Cefotaxime (FOT)

8

2

16

0.25

Cefotaxime/clavulanic acid (F/C)

8

2

2

0.25*

Cefoxitin (FOX)

4

4

4

8

Ceftazidime (TAZ)

64

16

16

1

Ceftazidime/clavulanic acid (T/C)

32

16

32

1

Ertapenem (ETP)

0.06

0.03

0.03

0.03*

Imipenem (IMI)

1

0.5

0.5

1

Meropenem (MERO)

0.06

0.06

 ≤ 0.03

0.125

Temocillin (TRM)

16

16

32

8

  1. *in the absence of cut-offs for K. pneumoniae, values for Escherichia coli have been used
  2. Resistances are highlighted in bold