Table 1 Patient characteristics
MTC | CTC | Total | |
|---|---|---|---|
(N = 208) | (N = 164) | (N = 372) | |
Age (at inclusion) | |||
Median (IQR) | 61.0 (16) | 59.0 (15) | 59.0 (16) |
Sex | |||
Male, n (%) | 121 (58.2) | 104 (63.4) | 225 (60.5) |
Underlying haematologic malignancy, n (%) | |||
Acute leukaemia/blastic transformation | 141 (67.8) | 78 (47.6) | 219 (58.7) |
Acute lympoblastic leukemia | 9 (4.3) | 4 (2.4) | 13 (3.5) |
Chronic lymphoblastic leukemia | 0 (0.0) | 1 (0.6) | 1 (0.3) |
Lymphoma | 24 (11.5) | 34 (20.7) | 58 (15.6) |
Myelofibrosis | 9 (4.3) | 2 (1.2) | 11 (3.0) |
Plasma cell disorders | 25 (12.0) | 45 (27.4) | 70 (18.8) |
Received conditioning chemotherapy for stem cell transplantation | 62 (29.8) | 20 (12.2) | 82 (22.0) |
Amount of chemotherapy courses causing high-risk neutropenia included per patient | |||
1 | 108 | 112 | 220 |
2 | 50 | 26 | 76 |
3 | 44 | 21 | 65 |
4 | 4 | 5 | 9 |
5 | 2 | 0 | 2 |
Febrile neutropenic episodes | 348 | 325 | 673 |
Febrile neutropenic episodes included per patient | |||
1 | 117 | 89 | 206 |
2 | 56 | 32 | 88 |
3 | 25 | 19 | 44 |
4 | 7 | 12 | 19 |
5 | 2 | 7 | 9 |
6 | 1 | 4 | 5 |
7 | 0 | 1 | 1 |
Central catheter, n (%) | |||
PICC | 192 (92.3) | 3 (1.8) | 195 (52.4) |
CVC | 7 (3.3) | 158(96.3) | 165(44.4) |
PICC and CVC | 6 (2.9) | 1 (0.6) | 7 (1.9) |
Unknown/Missing data | 3 (1.4) | - | 3 (0.8) |
None | 0 (0.0) | 2 (1.2) | 2 (0.5) |
Total parenteral nutrition, n (%) | 61 (29.3) | 104 (63.4) | 165 (44.4) |
Neutropenic episode duration in days, median (IQR) | 26 (14) | 17 (14) | 23 (16) |
ICU transfer/all-cause mortality within 30 days | 35 (16.8) | 34 (20.7) | 69 (18.5) |