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Table 1 Susceptibility of Klebsiella pneumoniae to antimicrobial agents from 2012 to 2019

From: Risk factors and mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection in a tertiary-care hospital in China: an eight-year retrospective study

Antimicrobial agents

2012 (n = 58)

2013 (n = 64)

2014 (n = 71)

2015 (n = 83)

2016 (n = 88)

2017 (n = 96)

2018 (n = 115)

2019 (n = 131)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

R (%)

S (%)

Ampicillin

89.7

1.72

98.4

0

100.0

0

100.0

0

100.0

0

100.0

0

100.0

0

100.0

0

Ampicillin-sulbactam

43.1

53.4

43.8

56.2

43.7

56.3

45.8

54.2

47.7

52.3

47.9

52.1

50.4

49.6

52.7

47.3

Piperacillin-tazobactam

22.4

74.1

28.1

68.8

25.4

71.8

30.1

69.9

30.7

68.2

35.4

62.5

36.5

61.7

37.4

58.8

Cefoperazone-sulbactam

20.7

72.4

26.6

71.9

24.0

74.6

28.9

69.9

31.8

68.2

34.4

61.5

33.9

63.5

34.4

62.6

Cefazolin

53.4

46.6

45.3

54.7

52.1

47.9

49.4

50.6

51.1

48.9

53.1

46.9

52.2

47.8

53.4

46.6

Cefuroxime

44.8

55.2

46.9

53.1

47.9

52.1

47.0

53.0

47.7

52.3

47.9

52.1

49.6

50.4

51.1

48.9

Ceftazidime

27.6

72.4

26.6

71.9

26.8

73.2

31.3

68.7

31.8

68.2

35.4

61.5

35.7

64.3

38.2

61.8

Ceftriaxone

36.2

63.8

40.6

59.4

40.8

59.2

45.8

54.2

45.5

54.5

49.0

51.0

51.3

48.7

52.7

47.3

Cefepime

27.6

72.4

29.7

70.3

31.0

69.0

30.1

69.9

34.1

65.9

36.5

63.5

34.8

65.2

37.4

62.6

Cefotetan

19.0

77.6

25.0

75.0

22.5

77.5

27.7

72.3

33.0

67.0

34.4

65.6

37.4

62.6

38.9

61.1

Aztreonam

32.8

67.2

37.5

62.5

36.6

63.4

38.6

60.2

39.8

60.2

41.7

56.3

36.5

63.5

41.2

58.8

Ertapenem

19.0

81.0

21.9

78.1

22.5

77.5

27.7

72.3

30.6

69.3

32.3

67.7

33.9

66.1

36.6

63.4

Imipenem

20.7

79.3

20.3

79.7

22.5

77.5

26.5

73.5

30.6

69.3

30.2

69.8

33.0

67.0

35.9

64.1

Meropenem

20.7

79.3

21.9

78.1

22.5

77.5

27.7

72.3

29.5

70.5

31.3

68.7

33.9

66.1

36.6

63.4

Amikacin

11.1

87.9

12.5

87.5

16.9

83.1

19.3

79.5

19.3

80.7

20.8

79.2

22.6

77.4

24.4

75.6

Gentamicin

34.5

65.5

28.1

71.9

26.8

73.2

30.1

68.7

23.9

76.1

25.0

75.0

24.3

75.7

27.5

72.5

Tobramycin

20.7

69.0

18.8

76.6

15.5

80.3

22.9

77.1

22.7

75.0

21.9

68.8

19.1

70.4

24.4

68.7

Ciprofloxacin

31.0

58.6

35.9

62.5

40.8

56.3

38.6

61.4

37.5

60.2

38.5

59.4

35.7

60.9

40.5

54.2

Levofloxacin

29.3

62.1

28.1

71.9

25.4

74.6

26.5

72.3

31.8

67.0

33.3

66.7

33.9

63.5

35.1

63.4

SMZ-TMP

32.8

67.2

32.8

67.2

32.4

67.6

34.9

65.1

35.2

64.8

36.5

63.5

38.3

61.7

38.9

61.1

Tigecycline

    

0

98.9

1.0

97.9

2.6

95.7

3.1

95.4

    
  1. R Resistance, S susceptible, SMZ-TMP Trimethoprim-sulfamethoxazole