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Table 1 Characteristics of the study population and peripherally inserted central catheters (PICC)

From: Clinical factors associated with peripherally inserted central catheters (PICC) related bloodstream infections: a single centre retrospective cohort

 

Total (N = 901) N (%) or median (IQR)

No PR-BSI (N = 828) N (%) or median (IQR)

PR-BSI (N = 73) N (%) or median (IQR)

Patients, N

783

713

70

Sex ratio M/F

500/401

461/367

37/33

Age (year)

70.9 (IQR, 59.4–79.8)

71.0 (IQR, 59.8–80.5)

69.8 (IQR, 58.8–74.1)

Body Mass Index (kg/m2)

24.5 (IQR, 21.2–28.9)

23.8 (IQR, 20.7–28.1)

24.4 (IQR, 21.1–28.7)

Charlson comorbidity index

6 [3,4,5,6,7,8,9]

6 [3,4,5,6,7,8]

7 [4,5,6,7,8,9,10]

Main comorbidities

Corticosteroids

141 (18%)

112 (16%)

29 (41%)

Immunosuppressors

101 (13%)

78 (11%)

23 (33%)

Solid tumour

142 (18%)

129 (18%)

13 (19%)

Metastatic solid tumour

178 (23%)

151 (21%)

27 (38%)

Haematological malignancy

69 (9%)

51 (7%)

18 (26%)

Leukaemia

46 (6%)

36 (5%)

10 (14%)

Lymphoma

23 (3%)

15 (2%)

8 (11%)

PICC lumen

1 lumen

712 (79%)

669 (81%)

43 (59%)

2 lumens

189 (21%)

159 (19%)

30 (41%)

Reason for PICC insertion

Antimicrobial therapy

408 (45%)

397 (48%)

11 (15%)

Chemotherapy

240 (27%)

201 (24%)

39 (53%)

Difficult venous access

154 (17%)

143 (17%)

11 (15%)

Total parenteral nutrition

52 (6%)

44 (5%)

8 (11%)

Iterative venous access

47 (5%)

43 (5%)

4 (5%)

Insertion site

Left basilic vein

470 (52%)

436 (53%)

34 (47%)

Right basilic vein

135 (15%)

124 (15%)

11 (15%)

Left brachial vein

209 (24%)

189 (22%)

21 (29%)

Right brachial vein

72 (8%)

67 (8%)

5 (7%)

Left cephalic vein

12 (1%)

10 (1%)

2 (3%)

Right cephalic

1 (< 1%)

1 (< 1%)

0 (0%)

Femoral

1 (< 1%)

1 (< 1%)

0 (0%)

PICC maintenance (days)

21 (IQR, 9–43]

20 (IQR, 9–41]

30 (IQR, 16–76)

Reason for PICC removal

End of IV therapy

529 (59%)

529 (64%)

0 (0%)

Accidental withdrawal

61 (7%)

60 (7%)

1 (1%)

PR-BSI suspicion

124 (14%)

62 (7%)

62 (85%)

Positive blood culture

5 (1%)

2 (<1%)

3 (4%)

Vein thrombosis

18 (2%)

17 (2%)

1 (<1%)

PICC occlusion

12 (1%)

11 (1%)

1 (<1%)

Local inflammation

9 (1%)

8 (1%)

1 (<1%)

Port implantation

26 (3%)

25 (3%)

1 (<1%)

Death

117 (13%)

114 (14%)

3 (4%)

  1. BSI Bloodstream infection, COPD Chronic obstructive pulmonary disease, IQR Interquartile range, PR-BSI PICC related bloodstream infection, IV Intravenous