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Table 4 Factors independently associated with peripherally inserted central catheters (PICC) related bloodstream infection (PR-BSI), and predictive values of clinical signs for PR-BSI

From: Clinical factors associated with peripherally inserted central catheters (PICC) related bloodstream infections: a single centre retrospective cohort

 

Multivariate analysis

Diagnostic ability of clinical signs

Variables

Hazard ratio

95% CI

p-value

Sensitivity

Specificity

PPV

NPV

Patient conditions

Immunosuppr. therapy1

1.07

0.80–1.43

0.63

–

–

–

–

Malignancy2

1.08

0.67–1.75

0.75

–

–

–

–

Dementia

1.62

0.18–14.58

0.67

–

–

–

–

Clinical signs

       

Local signs

       

Pain

0.55

0.17–1.81

0.33

9.6%

98.7%

38.8%

92.5%

Rash

2.82

0.82–9.69

0.10

8.2%

99.6%

66.7%

92.5%

Systemic signs

Fever

13.21

6.00–29.11

 < 0.001

83.6%

93.0%

51.3%

98.5%

Chills

3.66

1.92–6.99

 < 0.001

64.4%

97.2%

67.1%

96.9%

Dyspnoea

1.24

0.53–2.94

0.62

12.0%

99.4%

64.3%

93.0%

PICC duration ≥ 28 days

–

–

–

53.4%

62.8%

11.2%

93.9%

  1. 1at least one of the following: corticosteroids, azathioprine, mycophenolate mophetil, tacrolimus, ciclosporin. 2solid tumour or haematological malignancy. PPV Positive predictive Value, NPV Negative Predictive Value, 95% CI 95%confidence interval
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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