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Table 10 Polymyxin (colistin and polymyxin B) resistance (R) estimates and data for Klebsiella spp. isolates from studies including samples from 2010 and later

From: Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa

    

Findings in reports from all study years meeting criteria for generalizability

Resistance estimate category

Nations

Number of reports

Specimens in all reports

Any R

Reports meeting criteria

Total specimens meeting criteria

Range of specimens among studies

Resistant specimens (#)

Resistant specimens (%)

Resistant range (%)

Median R

Algeria

17

1056

Y

6

1015

13–608

2

0.2

0–4.3

0

Low

Angola

1

24

N

0

0

-

-

-

-

-

Insufficient isolates—resistance not detected

Benin

2

51

N

2

51

10–41

0

0

0–0

N/A*

Insufficient isolates—resistance not detected

Burkina Faso

1

5

N

0

0

-

-

-

-

-

Insufficient isolates—resistance not detected

Cameroon

1

3

N

0

0

-

-

-

-

-

Insufficient isolates—resistance not detected

Egypt

27

1084

Y

10

605

14–183

11

1.8

0–50

0

Low

Ethiopia

4

53

Y

3

51

10–30

17

33.3

0–90

N/A*

Insufficient isolates—resistance detected

Ghana

1

38

Y

1

38

-

5

13.2

-

N/A*

Insufficient isolates—Resistance detected

Kenya

1

5

N

0

0

-

-

-

-

-

Insufficient isolates—Resistance not detected

Libya

8

179

Y

3

136

24–76

6

4.4

0–25

0

Low

Malawi

2

8

N

0

0

-

-

-

-

-

Insufficient isolates—resistance not detected

Mauritania

1

137

Y

1

137

-

1

0.7

-

0.8

Low

Mauritius

2

119

Y

1

118

-

0

0

-

0

Low

Morocco

7

245

Y

4

232

10–118

28

12.1

0–22.9

0.6

Low

Niger

1

4

Y

0

0

-

-

-

-

-

Insufficient isolates—resistance detected

Nigeria

9

95

Y

4

80

10–32

0

0

0–0

N/A *

Insufficient isolates—Resistance detected

Senegal

1

34

Y

1

34

-

3

8.8

-

N/A*

Insufficient isolates—resistance detected

South Africa

15

2286

Y

7

1682

10–839

18

1.1

0–2.9

0

Low

Sudan

1

50

Y

0

0

-

-

-

-

-

Insufficient isolates—resistance detected^

Tanzania

2

59

Y

0

0

-

-

-

-

-

Insufficient isolates—resistance detected

Togo

2

31

N

1

30

-

0

0

-

N/A*

Insufficient isolates—resistance not detected

Tunisia

20

4250

Y

11

4148

11–2826

60

1.4

0–6.2

0.5

Low

Uganda

2

20

Y

1

12

-

3

25

-

N/A*

Insufficient isolates—resistance detected

All reporting countries

128

9836

Y

56

8369

10–2826

154

1.8**

–

–

–

  1. Y one or more resistant isolates identified phenotypically or genotypically
  2. N no resistant isolates identified phenotypically or genotypically
  3. ^Only genotypic resistance reported
  4. *Insufficient isolates (< 100) for polymyxin resistance estimate
  5. **Calculation should not be considered an estimate of overall resistance due to varying totals of specimens meeting criteria across nations
  6. -Data not available
  7. –Not calculated