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Fig. 3 | Antimicrobial Resistance & Infection Control

Fig. 3

From: Genome profiling of uropathogenic E. coli from strictly defined community-acquired UTI in paediatric patients: a multicentric study

Fig. 3

Comparison of mobile genetic elements among the Escherichia coli isolates. a The figure shows the presence of the mobile elements carrying similar AMR gene cassettes and draws the comparison of these elements between isolates ID5, ID4, ID7 and ID3. All these 4 isolates were seen carrying Tn2680 with the same AMR genes with high similarity to each other bracketed by a set of IS26. The horizontal lines in the background represent the transposons with forward orientation (blue) and reverse orientation (green). The squares represent the insertion sequences that form the transposon and the arrows represent the genes carried by the transposons. The dark gray shaded area indicates the regions with high identity between the isolates. b The region inside the box has been zoomed in to show the co-integrated mobile genetic elements. The partial fragments of ISEcp1(105 bp, 717 bp) were seen lying in close proximity to the insertion sequences (IS26) of Tn2680 and surrounding the gene cassette containing blaNDM-5, aadA2, sul1, dfrA12 and qacE. Other resistance genes such as aac(6ʹ)-lb-cr, blaOXA-1, catB3 and blaCTX-M15 with a complete ISEcp1 fragment was found downstream of the 717 bp partial fragment

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