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Table 5 Comparison of hospital costs stratified by number of HAI episodes

From: Incremental costs of hospital-acquired infections in COVID-19 patients in an adult intensive care unit of a tertiary hospital from a low-resource setting

Variable

no HAI

(n = 158)

1 HAI

(n = 37)

p a

≥ 2 HAIs

(n = 19)

pb

p c

Total costs, €

1650.4 (237–9700.0)

3343.4 (1474.0-12211.0)

< 0.001

7336.9 (1347.0-13792.0)

< 0.001

< 0.001

 Services

423.3 (82.8-1488.4)

682.7 (326.1-1513.5)

< 0.001

1253.0 (503.7-2587.7)

< 0.001

< 0.001

 Materials

106.5 (7.5-478.5)

232.7 (52.7-527.7)

< 0.001

342.8 (101.1-1073.4)

< 0.001

0.005

 Laboratory testing

169.7 (7.8-761.7)

305.5 (149.8-896.8)

< 0.001

444.8 (144-6-1351.6)

< 0.001

0.027

 Occupancy cost

131.4 (39.4–736.0)

210.3 (78.9-657.2)

0.004

407.4 (118.3-1038.4)

< 0.001

0.001

 Medications

728.2 (50.1-6835.7)

1793.3 (493.7-9205.4)

< 0.001

4067.7 (455-9-8446.1)

< 0.001

< 0.001

  Antibiotics

130.2 (0.0-1089.0)

358.1 (66.0-1296.3)

< 0.001

1226.7 (197.1-3047.4)

< 0.001

< 0.001

  Non-antibiotic drugs

568.6 (30.9-6588.1)

1430.2 (326.4-8406.7)

< 0.001

2306.4 (258.9-7437.4)

< 0.001

0.002

LOS (days)

10.0 (3–55)

16.0 (6–55)

0.003

31.0 (9–80)

< 0.001

0.001

Mortality

81 (51.3%)

35 (94.6%)

< 0.001

15 (78.9%)

< 0.001

0.079

  1. HAI hospital-acquired infection; LOS length of stay; a difference between costs in patients without HAIs and with 1 HAI; b difference between costs in patients with 1 HAI and in ≥ 2 HAIs; cdifference between costs in patients with 1 and  ≥ 2 HAIs