Table 1 Characteristics of included studies
Reference | Study | Study place | Data type | Setting and sample source | Sample size | No of recovered isolates | Antibiotics used |
|---|---|---|---|---|---|---|---|
[11] | Akortha and Ikenebomeli, 2010 | South south (Benin) | Primary, | Hospital: Nasal | 52 | 20 | CPR, TET, CHL, ERY, AMP, OFL |
[12] | Idris et al., 2018 | Northwest (Kano) | Primary | Hospital: Blood | Â | 195 | MET, CPR, TET, ERY, GEN, CLIN, CEF |
[13] | Stanley et al., 2013 | Southsouth (Porthacourt) | Primary | Hospital: Vaginal swab | 265 | 74 | MET, CPR, TET, ERY, AMP, GEN |
[14] | Odu and Okonkwo, 2012 | Southsouth (Porthacourt) | Primary | Urban:Nasal | 100 | 32 | MET, CIPRO, TET, ERY, AMP, GEN, CLIN, CXC, COT, STR |
[15] | Isibor and Otabor, 2014 | Southsouth (Edo) | Primary | Urban: Nasal | 100 | 32 | AMO, CTR, CRX |
[16] | Nworie, 2013 | Southeast (Ebonyi) | Primary | Urban: Nasal | 87 | 20 | VAN, CPR, TET, ERY, AMP, OFL, GEN, COT, CTR |
[17] | Egbuobi et al., 2014 | Southeast (Imo) | Primary | Hospital: Different clinical samples | 200 | 76 | MET |
[18] | Olowo-Okere et al., 2017 | Northwest | Primary | Hospital: Wound | 38 | 20 | CPR, ERY, AMO, GEN, NOR |
[19] | Olorode et al. 2021 | Southsouth (Bayelsa) | Primary | Hospital: Different clinical samples | 250 | 25 | MET, CPR, CHLERY, AMP, AMO, GEN, RIF, STR, NOR |
[20] | Onanuga and Awhowho, 2012 | Southsouth (Bayelsa) | Primary | Hospital: Urine | 200 | 46 | VAN, CPR, TET, CHL, AMP, OFL, GEN, COT, AUG, CRX, CEF |
[21] | Ayodeji and Omoniyi, 2009 | Southwest (Ogun) | Primary | Hospital; Different clinical samples | 107 | 107 | VAN, CPR, TET, ERY, AMP, AMO, GEN, CXC, COT, STR, CAZ, PEN |
[22] | Onanuga and Onaolapo, 2008 | Nortwest (Kaduna) | Primary | Urban: Urine | 150 | 54 | VAN, MET, CPR, AMP, OFL, GEN, CLIN |
[23] | Chigbu and Ezeronye, 2003 | Southeast (Abia) | Primary | Hospital: Ear and nasal | 70 | 38 | CPR, TET, CHL, ERY, AMP, AMO, GEN, RIF, CXC, PEN |
[24] | Enabule et al., 2007 | Southsouth | Primary | Hospital: Urine | Â | 80 | CPR, TET, ERY, AMP, GEN |
[25] | Yah et al., 2009 | Southsouth (Benin) | Primary | Hospital: Wound | 153 | 86 | CPR, TET, CHL, ERY, GENCXC, COT |
[26] | Onwubiko and Saidiq, 2011 | Northwest (Kano) | Secondary | Hospital: Different clinical samples | Â | 150 | CPR, TET, ERY, AMP, AMO, OFL, GENCXC, STR, PEN, CAZ |
[27] | Onanuga and Temedie, 2011 | SOuthsouth | Primary | Urban: Nasal | 120 | 40 | VAN, CPR, CHL, ERY, AMP, AMO, OFL, AUG, CRX, CEF |
[28] | Onanuga et al., 2005 | Northcentral (Abuja) | Primary | Hospital: Urine | 150 | 60 | VAN, MET, CPR, AMP, OFL, GEN, CLIN |
[29] | Akanbi and Mbe, 2013 | Northcentral (Abuja) | Primary | Hospital: Different clinical samples | Â | 214 | VAN, MET, ERY, AMP, OFL, GEN |
[30] | Terry et al., 2011 | Nortwest | Secondary | Hospital: Different clinical samples | Â | 194 | MET, TET, CHL, ERY, AMP, GEN, STR, CAZ, PEN, CTR |
[31] | Iroha et al., 2012 | Southeast (Ebonyi) | Primary | Hospital: Nasal | Â | 105 | VAN, CPR, ERY, CLIN, CXC, COT, PEN |
[32] | Eke et al., 2012 | Southsouth (Edo) | Primary | Urban: Nasal and ear | 100 | 39 | MET, CPR, TET, AMP, PEN |
[33] | Ekundayo and Ndubuisi, 2015 | Southeast (Abia) | Primary | Hospital: Different clinical samples | 100 | 113 | TET, CHL, ERY, AMP, GEN, CXC, COT, AUG, STR, PEN |
[34] | Obasuyi and Akerele, 2015 | Southsouth (Edo) | Secondary | Hospital: Different clinical samples | Â | 75 | MET |
[35] | Akerele et al., 2015 | Southsouth (Edo) | Primary | Urban: Nasal | 200 | 99 | MET, CPR, ERY, AMP, AMO, GEN, STR, CTR |
[36] | Badger-Emeka et al., 2014 | Southeast 9Enugu) | Primary | Hospital: Wound | 34 | 34 | VAN, MET, TET, CHL, ERY, AMO, OFL, GEN, CXC, COT, AUG, STR |
[37] | Ayeni et al., 2015 | Southsouth (Bayelsa) | Secondary | Urban: Nasal | 185 | 185 | ERY, AMP, PEN, CTR, NOR |
[38] | Torimino et al., 2012 | Southwest (Oyo) | Primary | Urban: Different clinical samples | 50 | 40 | CPR, TET, CHL, ERY, AMO, OFL, GENCXC, COT, STR, CTR |
[39] | Bale et al., 2019 | Southwest (Kwara) | Primary | Urban: Nasal | 113 | 42 | TET, ERY, OFL, CXC, AUG, CTR, CTR |
[40] | Adesoji et al., 2019 | Nortwest (Katsina) | Primary | Urban: Different clinical samples | 120 | 120 | ERY, OFL, GEN, CXC, AUG, CAZ, CRX, CTR |
[41] | Ariom et al., 2011 | Southeast (Ebonyi) | Primary | Hospital: Different clinical samples | 709 | 84 | MET, CPR, TET, GEN, CAZ, PN |
[42] | Ajani et al., 2020 | Southwest (Ogun) | Primary | Urban: Nasal | 200 | 20 | MET |
[43] | Olonrunfemi et al., 2020 | Northcentral | Primary | Urban: Urine | 217 | 73 | MET |
[44] | Onanuga et al., 2021 | Northeast | Primary | Urban: Nasal | 262 | 46 | TET, ERY, AMO, GENCOT |
[45] | Ramalan et al., 2020 | Northcentral (Nasarawa) | Primary | Hospital: Urine | 202 | 62 | CPR, CHL, ERY, AMP, AMO, GEN, STR |
[46] | Udobi et al., 2013 | Northwest (Kaduna) | Primary | Hospital: Skin and wound | 217 | 69 | CPR, AMO, GEN, CTR |
[47] | Obasola et al., 2010 | Southwest (Oyo) | Primary | Urban: Different clinical samples | 50 | 50 | TET, CHL, ERY, AMO, GENCXC, COT, AUG |
[48] | Moses et al., 2017 | Southsouth (Uyo) | Primary | Hospital: Nasal | 130 | 41 | VAN, CPR, TET, ERY, GENCLIN, CEF |
[49] | Nsofor et al., 2015 | Southeast (Imo) | Primary | Urban: Nasal | 270 | 152 | TET, CHL, ERY, GEN |
[50] | Adetayo et al., 2014 | Southwest (Oyo) | Primary | Hospital: Different clinical samples | 150 | 66 | VAN |
[51] | Ejikeugwu et al., 2018 | Southeast (Ebonyi) | Secondary | Hospital: Different clinical samples | Â | 39 | ERY, GEN, CLIN, CXC, CEF |
[52] | Anucha et al., 2021 | Southeast (Anambra) | Primary | Hospital: Urine | 236 | 62 | VAN, TET, ERY, AMO, OFL, GEN, CRX |
[53] | Agwu et al., 2010 | Southsouth (Edo) | Primary | Hospital: Wound | 220 | 66 | VAN, RIF, CRX, CTR |
[54] | Adesida et al., 2016 | Southwest (Lagos) | Primary | Urban: Nasal | 230 | 50 | ERY, AMO, OFL, GEN, CXC, CAZ, CRX, CTR |
[55] | Mofolorunsho et al., 2015 | Northcentral (Kogi) | Primary | Hospital: Different clinical samples | 100 | 22 | CPR, TET, ERY, AMO, OFL, GEN, COT, STR |
[56] | Osiyemi et al., 2018 | Southwest (Ogun) | primary | Hospital: Different clinical samples | 338 | 161 | VAN, CPR, TET, ERY, OFL, GEN, COT, AUG, CAZ, CEF, CTR |
[57] | Ibe et al., 2014 | Southeast (Abia) | Primary | Hospital: Different clinical samples | 84 | 69 | MET |
[58] | Onaolapo et al., 2016 | Northwest(Kaduna) | Primary | Hospital: Wound and skin | 65 | 22 | VAN, CPR, ERY, AMP, AMO, CLIN, CEF, CTR |
[59] | Ugwu et al., 2016 | Southsouth (Delta) | Primary | Urban: Nasal | 300 | 218 | MET |
[60] | Tula et al., 2016 | Northeast | Primary | Hospital: Different clinical samples | 100 | 45 | CPR, AMO, OFL, GEN, CXC, CAZ, CRX, CTR |
[61] | Anyanwu et al., 2013 | Northwest (Kaduna) | Primary | Hospital: Skin | 400 | 69 | VAN, CHL, CAZ, CTR |
[62] | Onyeagwara et al., 2014 | Southsouth (Edo) | Primary | Hospital: Nasal | 50 | 25 | CPR, ERY, AMP, AMO, GENSTR, CAZ |
[63] | Ngwai and Bakare, 2012 | Northcentral (Nasarawa) | Primary | Urban: Urine | 300 | 60 | CHL, TET, ERY, AMO, GENCXC, STR |
[64] | Umar et al., 2015 | Nortwest (Kaduna) | Primary | Hospital: Skin and nasal | 40 | 34 | CPR, CHL, ERY, AMO, GEN, RIF, STR |
[65] | Obajuluwa et al., 2015 | Northwest (Kaduna) | Primary | Hospital: Wound and skin | 100 | 39 | VAN, CPR, ERY, AMP, AMO, GENCEF, CTR |
[66] | Iduh et al., 2015 | Southsouth | Primary | Hospital: Wound | 300 | 64 | TET, AMP, GEN, STR |
[67] | Ibanga et al., 2020 | Southsouth (Akwa-Ibom) | Primary | Hospital Different clinical samples | 100 | 28 | TET, CHL, ERY, AMO, GEN, STR |
[68] | Emeakaroha et al., 2017 | Southeast (Imo) | Primary | Urban: Nasal and throat | 54 | 28 | CHL, ERY, AMO, AMP, COT, CRX, PEN |
[69] | Bisi-Johnson et al., 2005 | Southwest (Oyo) | Primary | Hospital: Different clinical samples | 86 | 97 | TET, CHL, AMP, AMO, GENCXC, STR, PEN |
[70] | Ayepola et al., 2015 | Southwest (Lagos) | Secondary | Hospital:Nasal | ` | 217 | TET, GEN, PEN |
[71] | Odogwu et al., 2019 | Northcentral (Abuja) | Primary | Hospital: Different clinical samples | 360 | 55 | CPR, ERY, AMP, GEN, RIF, CLIN, STR, TRIM |
[72] | Adeiza et al., 2020 | Northwest (Sokoto) | Primary | Hospital: Nasal | 378 | 33 | TET, CHL, ERY, GEN, CLIN, CAZ, CEF, TRIM |
[73] | Ismail et al., 2015 | Northeast (Borno) | Primary | Urban: Different clinical samples | 110 | 42 | CPR, CHL, ERY, AMO, GEN, RIF, STR, NOR |
[74] | Ibrahim et al., 2018 | Northwest (Kano) | Primary | Hospital: Wound and ear | 150 | 71 | CPR, TET, ERY, GEN, CLIN, CEF, TRIM, CTR |
[75] | Olowe et al., 2013 | Southwest (Ekiti) | Primary | Hospital: Different clinical samples | Â | 208 | VAN, MET, TET, ERY, GEN, PEN, CEF |
[76] | Oche et al., 2021 | Northwest (Kano) | Primary | Hospital: Different clinical samples | 140 | 26 | MET, CPR, TET, ERY, AM, GEN, CEF, TRIM, NOR |
[77] | Onelum et al., 2015 | Southwest (oyo) | Primary | Hospital: Different clinical samples | 246 | 102 | MET, CHL, GEN, CLIN, CAZ, CEF |
[78] | Akinduti et al., 2021 | Southwest (Ogun) | Primary | Hospital: Different clinical samples | 256 | 68 | VAN, CPR, TET, ERY, AMO, OFL, GEN, CAZ, CRX, TRIM |
[79] | Oladipo et al., 2019 | Southwest (Osun) | Primary | Hospital: Different clinical samples | Â | 25 | MET, CPR, ERY, AMO, GEN, OFL, CXC, CEF, CRX |
[80] | Ogefere et al., 2020 | Southsouth (Edo) | Secondary | Urban: Different clinical samples | Â | 556 | MET |
[81] | Motayo et al., 2012 | Southwest (Ogun) | Â | Hospital: Different clinical samples | Â | 50 | MET, TET, CHL, ERY, AMO, GEN, CTR |
[82] | Onyeka et al., 2021 | Southsouth (Rivers) | Primary | Urban: | 150 | 78 | ERY, OFL, GENCXC, AUG, CAZ, CRX, CTR |
[83] | Ugwu et al., 2009 | Southeast (Enugu) | Primary | Nasal | 100 | 53 | TET, CHL, AMO, GEN, COT, AUG |
[84] | Nsofor et al., 2016 | Southeast (Abia) | Primary | Hospital: Different clinical samples | 424 | 104 | CPR, TET, CHL, ERY, AMP, CAZ, PEN |
[85] | Mbim et al., 2017 | Southsouth (Cross river) | Primary | Hospital: Nasal | 150 | 42 | MET, CPR, CHL, ERY, AMO, GEN, RIF, CEF, NOR |
[86] | Ogbolu et al., 2015 | Southwest (Osun) | Secondary | Hospital: Different clinical samples | Â | 116 | VAN, TET, ERY, GEN, CAZ |
[87] | Osinupebi et al., 2018 | Southwest (Ogun) | Primary | Hospital: Different clinical samples | 338 | 161 | VAN, CPR, TET, ERY, OFL, GEN, COT, AUG, CAZ, CEF, CTR |
[88] | Ajoke et al., 2012 | Northcntral (Plateau) | Primary | Urban: Nasal | 200 | 98 | TET, ERY, AMP, AMO, GEN |
[89] | Onyebueke et al., 2019 | Southeast (Enugu) | Primary | Hospital: Urine | 818 | 89 | CPR, ERY, AMO, GEN, STR, NOR |
[90] | Adetutu et al., 2017 | Southwest (Ota) | Primary | Urban: Pimple | 20 | 20 | TET, CHL, ERY, GEN, CXC, COT, AUG, STR |
[91] | Bale et al., 2021 | Southwest (Kwara) | Primary | Hospital: Urine | 856 | 56 | MET, CPR, TET, CHL, ERY, AMO, OFL, GEN, AUG, CEF, CTR |
[92] | Nmema, 2017 | Southwest (Ondo) | Primary | Urban: Skin and nasal | 80 | 34 | ERY, GEN, CXC, AUG, CAZ, CRX, CTR |
[93] | Ike et al., 2016 | Southeast (Anambra) | Primary | Hospital: Nasal and hand | 261 | 142 | MET |
[94] | Ugwu et al., 2015 | Southeast (Anambra) | Primary | Hospital: Nasal | 100 | 68 | CPR, ERY, AMP, AMO, OFL, GEN, COT, STR, CTR |
[95] | Emeka- Nwabunnia et al., 2015 | Southeast (Imo) | Primary | Urban:Different clinical samples | Â | 59 | VAN |
[96] | Alli et al., 2012 | Southwest (Osun) | Secondary | hospital: different samples | Â | 116 | VAN, TET, ERY, AMO, GEN, CAZ |
[97] | Sadauki et al., 2022 | Northwest (Kano) | Primary | Hospital: Blood | 214 | 40 | MET, CPR, GEN, PEN, CTR |
[98] | O’ Malley et al., 2015 | Southwest (lagos) | Primary | Hospital: Different clinical samples | 73 | 38 | TET, ERY, GEN |
[99] | Emeka- Nwabunnia et al., 2019 | Southeast (Anambra) | Primary | Hospital: Different clinical samples | 83 | 25 | MET |
[100] | Ako-Nai et al., 2005 | Southwest (Osun) | Primary | Urban: Different clinical samples | Â | 112 | CPR, TET, CHL, ERY, GEN |
[101] | Frank-Peterside and Mukoro, 2010 | Southsouth (Rivers) | Primary | Hospital: Different clinical samples | Â | 50 | VAN, MET |
[102] | Yahaya et al., 2022 | Northwest (Kano) | Primary | Hospital: Different clinical samples | 200 | 31 | CPR, CHL, ERY, CLIN, COT, CEF |
[103] | Onanuga et al., 2019 | Southsouth (Bayelsa) | Primary | Urban: Nasal | 390 | 47 | CPR, TET, ERY, AMO, GEN, COT |
[104] | Ogini and Olayinka, 2021 | Southwest (Oyo) | Primary | Urban: Nasal | 700 | 223 | CPR, TET, ERY, AMO, GEN |
[105] | Nwankwo et al., 2010 | Northwest (Kano) | Secondary | Hospital: Different clinical samples | Â | 185 | MET, CPR, AMO, OFL, GEN, CAZ, CTR |
[106] | Olufunmiso et al., 2017 | Southwest (Ogun) | Primary | Hospital: Different clinical samples | 200 | 200 | ERY, OFL, GEN, COT, AUG, CAZ, CRX, CTR |
[107] | Olajide et al., 2012 | Northwest (Kano) | Secondary | Hospital: Different clinical samples | Â | 100 | ERY, AMO.CRX, NOR |