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Table 2 Antifungal susceptibility of the C. auris isolates (MICs in mg/L)

From: First report of Candida auris in Romania: clinical and molecular aspects

 

AMB

FLU

VOR

POS

ITR

MFG

AFG

Breakpoints*

≥ 2

≥ 32

-

-

-

≥ 4

≥ 4

Pt. 1

1

> 128

0.5

0.03

0.25

0.125

0.125

Pt. 2

4

128

4

8

4

0.125

0.25

Pt. 3

0.5

128

0.25

<=0.0078

<=0.0312

0.0312

0.0312

Pt. 4

0.5

64

0.25

<=0.0078

0.0312

0.0156

0.0156

Pt. 5

0.5

64

0.25

0.0156

<=0.0312

0.0625

0.0625

Pt. 6

0.5

> 128

0.5

0.0156

<=0.0312

0.0312

0.0625

Pt. 7

1

> 128

0.5

0.0156

0.0625

0.0625

0.0625

Pt. 8

1

> 128

0.5

0.0156

0.0625

0.0312

0.0312

Pt. 9

0.5

> 128

0.5

0.0156

<=0.0312

0.0156

0.125

Pt. 10

0.5

128

0.25

<=0.0078

<=0.0312

0.0312

0.0625

Pt. 11

0.5

64

0.5

0.0156

<=0.0312

0.0625

0.0625

Pt. 12

0.5

> 128

0.5

0.0156

<=0.0312

0.0625

0.0625

Pt. 13

0.5

>128

0.5

0.0156

<=0.0312

0.0625

0.0625

Pt. 14

0.5

> 128

0.5

0.0156

<=0.0312

0.0625

0.0625

Pt. 15

0.5

>128

0.5

0.0156

<=0.0312

0.0156

0.0625

Pt. 16

8

32

1

-

-

0.12

-

Pt. 17

>=16

32

1

-

-

0.12

-

Pt. 18

>=16

32

1

-

-

0.12

0.25

Range

0.5–16

32–128

0.25-4

0.0078-8

0.0312-4

0.0156–0.125

0.0156-0.25

  1. Abbreviations: AMB – Amphotericin B, FLU – Fluconazole, VOR – Voriconazole, POS – Posaconazole, ITR – Itraconazole, MFG – Micafungin, AFG – Anidulafungin.
  2. *CDC tentative breakpoints [9]