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Table 1 Clinicodemographic characteristics of the study population in each group at the time of blood culture

From: Empiric antimicrobial therapy in the intensive care unit based on the risk of multidrug-resistant bacterial infection: a single-centre case‒control study of blood culture results in Japan

 

All patients (n = 173)

R group (n = 129)

Control group (n = 44)

P value

Percentage of patients

100

74.6

25.4

 

 A: Resistant organism detected

15 (9)

15 (12)

0 (0)

 

 B: Antimicrobial use within 90 days

108 (62)

108 (84)

0 (0)

 

 C: Hospitalization within 90 days

87 (50)

87 (67)

0 (0)

 

Age

73 (63–81)

75 (65–81)

72 (58–77)

0.042

Female sex

69 (40)

55 (43)

14 (32)

0.206

Body mass index

22 (19–26)

22 (19–25)

24 (21–26)

0.005

Coexisting condition

 COPD

11 (6)

11 (9)

0 (0)

0.035

 Diabetes

67 (39)

46 (36)

21 (48)

0.156

 Dialysis

10 (6)

10 (8)

0 (0)

0.048

 Malignancy

36 (21)

30 (23)

6 (14)

0.175

 Allergy to antibiotics

5 (3)

3 (2)

2 (5)

0.376

Implantable devices

 Endovascular device

44 (25)

42 (33)

2 (5)

< 0.001

 Artificial joint

11 (6)

11 (9)

0 (0)

0.035

Admission source

< 0.001

 Emergency department

92 (53)

53 (41)

39 (89)

 

 General ward

81 (46)

76 (58)

5 (11)

 

SOFA score

8 (5–11)

8 (5–11)

7 (3–11)

0.529

Δ SOFA score

4 (1–8)

4 (0–8)

7 (3–11)

0.006

Lactate (mmol/L)

2.2 (1.3–3.9)

2.1 (1.3–3.5)

2.8 (1.3–4.9)

0.101

Sepsis

122 (70)

84 (65)

38 (86)

0.008

Septic shock

65 (37)

48 (37)

17 (38)

0.866

  1. Values are presented as the medians (IQRs), n, or n (%)
  2. P values were calculated with a two-tailed test