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Table 2 Clinical characteristics after blood culture

From: Empiric antimicrobial therapy in the intensive care unit based on the risk of multidrug-resistant bacterial infection: a single-centre case‒control study of blood culture results in Japan

 

All patients (n = 173)

R group (n = 129)

Control group (n = 44)

P value

Bacteraemia

65 (38)

45 (35)

20 (45)

0.211

 Septic shock

35 (20)

24 (18)

11 (25)

 

 Sepsis without shock

24 (13)

15 (11)

9 (20)

 

 No sepsis

6 (3)

6 (4)

0 (0)

 

Infection site

 Respiratory tract

54 (31)

41 (32)

13 (30)

 

 Urinary tract

15 (9)

12 (9)

3 (7)

 

 Catheter-related bloodstream

7 (4)

7 (5)

0 (0)

 

 Surgical site

3 (2)

2 (2)

1 (2)

 

 Clostridioides difficile

0 (0)

0 (0)

0 (0)

 

 Abdomen

20 (12)

13 (10)

7 (16)

 

 Central nervous system

3 (2)

2 (2)

1 (2)

 

 Other

21 (12)

16 (12)

5 (11)

 

 None

50 (29)

36 (28)

14 (32)

 

Empiric antimicrobial administration

141 (81)

108 (83)

33 (75)

0.198

De-escalation

59 (34)

44 (34)

15 (34)

0.998

Other treatment in ICU

 Intubation

45 (26)

33 (26)

12 (27)

0.825

 Tracheostomy

47 (27)

37 (29)

10 (23)

0.443

 Thoracic drainage

24 (14)

23 (18)

1 (2)

0.010

 IPPV

125 (72)

88 (68)

37 (84)

0.042

 NPPV

10 (6)

8 (6)

2 (5)

0.510

 HFNC

28 (16)

20 (16)

8 (18)

0.677

 CV

59 (34)

44 (34)

15 (34)

0.998

 PICC

26 (15)

20 (16)

6 (14)

0.765

 RRT

41 (24)

29 (22)

12 (27)

0.519

 IABP

20 (12)

12 (9)

8 (18)

0.112

 ECMO

11 (6)

9 (7)

2 (5)

0.437

 TTM

13 (8)

7 (5)

6 (14)

0.078

 Nutrition

  EN

76 (44)

57 (44)

19 (43)

0.908

  TPN

18 (10)

17 (13)

1 (2)

0.030

Number of days in the ICU

10 (6–16)

11 (6–19)

10 (7–15)

0.239

Number of days in the hospital

48 (25–81)

49 (25–82)

43 (29–71)

0.475

Ventilator-free days

22 (5–27)

22 (1–28)

22 (11–26)

0.836

28-day mortality

31 (18)

23 (18)

8 (18)

0.958

Discharge route-no. (%)

0.556

 Death

50 (29)

39 (30)

11 (25)

 

 Transferred to another hospital

71 (41)

54 (42)

17 (39)

 

 Discharged home

52 (30)

36 (28)

16 (36)

 

HAI after ICU discharge

 CDI (test n = 37)

3 (2)

3 (2)

0 (0)

0.412

 Candidemia

8 (5)

8 (6)

0 (0)

0.090

  1. Values are presented as the medians (IQRs), n, or n (%)