Table 5 Empiric antibiotic use
All patients (n = 173) | R group (n = 129) | Control group (n = 44) | P value | |
|---|---|---|---|---|
Antifungal | 15 (9) | 14 (11) | 1 (2) | 0.066 |
Anti-MRSA | 42 (24) | 30 (23) | 12 (27) | 0.592 |
Anti-Pseudomonas | 77 (45) | 61 (47) | 16 (36) | 0.208 |
Carbapenem | 30 (17) | 22 (17) | 8 (18) | 0.865 |
Anti-Pseudomonas penicillin | 37 (21) | 30 (23) | 7 (16) | 0.305 |
Anti-Pseudomonas cephem | 8 (5) | 7 (5) | 1 (2) | 0.351 |
Quinolone | 2 (1) | 2 (2) | 0 (0) | 0.555 |
Penicillin (excluding anti-Pseudomonas) | 29 (17) | 20 (16) | 9 (20) | 0.448 |
Cephem (excluding anti-Pseudomonas) | 31 (18) | 23 (18) | 8 (18) | 0.958 |
Macrolide | 3 (2) | 1 (1) | 2 (5) | 0.160 |
Sulfamethoxazole Trimethoprim | 3 (2) | 3 (2) | 0 (0) | 0.412 |
Metronidazole | 4 (2) | 4 (3) | 0 (0) | 0.305 |
Clindamycin | 2 (1) | 0 (0) | 2 (5) | 0.064 |
Antiviral | 2 (1) | 0 (0) | 2 (5) | 0.064 |
None | 32 (18) | 21 (16) | 11 (25) | 0.198 |
Bacteraemia | 65 (38) | 45 (35) | 20 (45) | |
Appropriate spectrum coverage | 48 (74) | 29 (64) | 19 (95) | 0.010 |
28-day mortality | 15(23) | 11 (24) | 4 (20) | 0.480 |