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Table 1 Demographic, epidemiological, and clinical characteristics of newborns with probable neonatal sepsis, distinguished by the type of neonatal sepsis

From: Exploring the use of cluster analysis to assess antibiotic stewardship in critically-ill neonates in a low resource setting

 

Overall

(n = 195)

EOS

(n = 146)

LOS

(n = 49)

p-Value*

Sex

   

0.319

 Female

83 (42.6%)

59 (40.4%)

24 (49.0%)

 

 Male

112 (57.4%)

87 (59.6%)

25 (51.0%)

 

Age (day)

   

< 0.001

 Median (IQR)

1.0 (1.0-5.5)

1.0 (1.0–2.0)

15.0 (10.0–21.0)

 

Weight at admission (g)

   

< 0.001

 Median (IQR)

2900 (2315–3300)

2710 (2100–3200)

3100 (2725–3690)

 

Place of delivery

   

0.008

 Inborn

119 (61.0%)

102 (69.9%)

17 (34.7%)

 

 Health center

49 (25.1%)

32 (21.9%)

17 (34.7%)

 

 Home

27 (13.8%)

12 (8.2%)

15 (30.6%)

 

Mode of delivery

   

0.002

 Spontaneous vaginal delivery

136 (69.7%)

92 (63.0%)

44 (89.8%)

 

 C- section

38 (19.5%)

33 (22.6%)

5 (10.2%)

 

 Vacuum

15 (7.7%)

15 (10.3%)

0 (0.0%)

 

 Assisted breech

6 (3.1%)

6 (4.1%)

0 (0.0%)

 

Premature rupture of membranes (N/A = 2)

   

0.004

 

41 (21.0%)

38 (26.0%)

3 (6.1%)

 

Chorioamnionitis (N/A = 2)

   

0.015

 

19 (9.7%)

19 (13.0%)

0 (0.0%)

 

Eclampsia (N/A = 2)

   

0.999

 

3 (1.5%)

3 (2.1%)

0 (0.0%)

 

Apgar 1st minute

   

0.109

 Median (IQR)

6.0 (3.0–8.0)

6.0 (3.0–7.0)

8.0 (3.5-9.0)

 

Apgar 5th minute

   

0.081

 Median (IQR)

7.0 (6.0–9.0)

7.0 (6.0–9.0)

9.0 (4.5–10.0)

 

Breath at birth (N/A = 2)

   

< 0.001

 

155 (79.5%)

108 (74.0%)

47 (95.9%)

 

Positive pressure ventilation at birth (N/A = 2)

   

< 0.001

 

39 (20.0%)

39 (26.7%)

0 (0.0%)

 

Oxygen given at birth (N/A = 2)

   

< 0.001

 

47 (24.1%)

47 (32.2%)

0 (0.0%)

 

Respiratory distress syndrome

   

0.412

 

90 (46.2%)

70 (47.9%)

20 (40.8%)

 

Length of stay

   

0.119

 Median (IQR)

7.0 (6.0–11.0)

8.0 (6.0–11.0)

7.0 (5.0–9.0)

 

Outcome at discharge

   

0.014

 Alive

161 (82.6%)

114 (78.1%)

47 (95.9%)

 

 Dead

26 (13.3%)

24 (16.4%)

2 (4.1%)

 

 Referred

8 (4.1%)

8 (5.5%)

0 (0.0%)

 
  1. * Fisherman-s exact and χ2 test, Mann-Whitney-U non-parametric test.
  2. ** Early (EOS) and late (LOS) neonatal sepsis.
  3. N/A = data were missing in the medical records.