Characteristics | n (%)b | 30-Days all-cause mortality | UOR (95% CI) | Pearson’s X2 | Pd | |
---|---|---|---|---|---|---|
Survived (26) n (%)c | Died (79) n (%)c | |||||
Age group (reference: 55–64 years) | ||||||
 < 45 | 9 (8.6) | 5 (55.6) | 4 (44.4) | 0.45 (0.10–2.12) | 10.40 | 0.04e,f |
 45–54 | 5 (4.8) | 0 (0) | 5 (100) | – |  |  |
 55–64 | 25 (23.8) | 9 (36) | 16 (64) | – |  |  |
 65–74 | 19 (18.1) | 5 (26.3) | 14 (73.7) | 1.58 (0.43–5.82) |  |  |
 ≥ 75 | 47 (44.8) | 7 (14.9) | 40 (85.1) | 3.21 (1.05–10.10) |  |  |
Sex (reference: female) | ||||||
 Male | 63 (60) | 15 (23.8) | 48 (76.2) | 1.14 (0.46–2.79) | 0.07 | 0.47 |
 Female | 42 (40) | 11 (26.2) | 31 (73.8) | – |  |  |
Department of infection acquisition (reference: internal medicine) | ||||||
 Intensive care unit | 83 (79) | 11 (13.3) | 72 (86.7) | 8.18 (1.90–35.23) | 33.26 | < 0.001e,g |
 Internal medicine | 9 (8.6) | 5 (55.6) | 4 (44.4) | – |  |  |
 Cardiac care unit | 10 (9.5) | 8 (80) | 2 (20) | – |  |  |
 Surgery | 1 (1) | 0 (0) | 1 (100) | – |  |  |
 Oncology | 2 (1.9) | 2 (100) | 0 (0) | – |  |  |
Past medical history (reference: no history of the related condition) | ||||||
 Hypertension | 68 (64.8) | 16 (23.5) | 52 (76.5) | 1.20 (0.48–3.01) | 0.157 | 0.69 |
 Diabetes mellitus | 61 (58.1) | 16 (26.2) | 45 (73.8) | 0.83 (0.33–2.05) | 0.168 | 0.68 |
 Neutropenia | 32 (30.5) | 5 (15.6) | 27 (84.4) | 2.18 (0.74–6.42) | 2.06 | 0.15 |
 Thrombocytopenia | 30 (28.6) | 2 (6.7) | 28 (93.3) | 6.59 (1.45–29.95) | 7.38 | < 0.001e |
 Chronic kidney disease | 36 (34.3) | 6 (16.7) | 30 (83.3) | 2.04 (0.74–5.66) | 1.92 | 0.17 |
 Coronary artery disease | 33 (31.4) | 9 (27.3) | 24 (72.7) | 0.82 (0.32–2.11) | 0.163 | 0.69 |
Previous hospitalization within the last 3 months (reference: no) | ||||||
 No | 94 (89.5) | 23 (24.5) | 71 (75.5) | – | 0.042 | 0.83 |
 Yes | 11 (10.5) | 3 (27.3) | 8 (72.7) | 0.86 (0.21–3.53) |  |  |
Previous antibiotics use within the last 3 months (reference: no) | ||||||
 No | 93 (88.6) | 24 (25.8) | 69 (74.2) | – | 0.477 | 0.49 |
 Yes | 12 (11.4) | 2 (16.7) | 10 (83.3) | 1.74 (0.36–8.51) |  |  |
Invasive procedures within 30 days prior to infection acquisition (reference: no) | ||||||
 No | 7 (6.7) | 4 (57.1) | 3 (42.9) | – | 4.22 | 0.04e |
 Yes | 98 (93.3) | 22 (22.4) | 76 (77.6) | 4.61 (0.96–22.15) |  |  |
Mechanical ventilation (reference: no) | ||||||
 No | 28 (26.7) | 18 (64.3) | 10 (35.7) | – | 32.01 |  < 0.001e |
 Yes | 77 (73.3) | 8 (10.4) | 69 (89.6) | 15.53 (5.35–45.02) |  |  |
Indwelling urethral catheterization (reference: no) | ||||||
 No | 32 (30.5) | 9 (28.1) | 23 (71.9) | – | 0.27 | 0.59 |
 Yes | 73 (69.5) | 17 (23.3) | 56 (76.7) | 1.29 (0.5–3.31) |  |  |
Central venous line (reference: no) | ||||||
 No | 47 (44.8) | 19 (40.4) | 28 (59.6) | – | 11.20 | 0.001e |
 Yes | 58 (55.2) | 7 (12.1) | 51 (87.9) | 4.94 (1.85–13.19) |  |  |
Major surgery (reference: no) | ||||||
 No | 86 (81.9) | 14 (16.3) | 72 (83.7) | – | 18.35 | 0.22 |
 Yes | 19 (18.1) | 12 (63.2) | 7 (36.8) | 0.11 (0.04–0.34) |  |  |
Prolonged total parenteral nutrition (reference: no) | ||||||
 No | 82 (78.1) | 22 (26.8) | 60 (73.2) | – | 0.85 | 0.35 |
 Yes | 23 (21.9) | 4 (17.4) | 19 (82.6) | 1.74 (0.53–5.69) |  |  |
Renal replacement therapy (dialysis) (reference: no) | ||||||
 No | 85 (81) | 24 (28.2) | 61 (71.8) | – | 2.89 | 0.08 |
 Yes | 20 (19) | 2 (10) | 18 (90) | 3.54 (0.76–16.44) |  |  |
Source of infection (reference: soft tissue/wound infection) | ||||||
 Respiratory infection | 86 (81.9) | 14 (16.3) | 72 (83.7) | 8.23 (2.34–28.88) | 19.13 | < 0.001e |
 Soft tissue/wound infection | 13 (12.4) | 8 (61.5) | 5 (38.5) | – |  |  |
 Blood stream infection | 5 (4.8) | 3 (60) | 2 (40) | 1.07 (0.13–8.79) |  |  |
 Urinary tract infection | 1 (1) | 0 (0) | 1 (100) | – |  |  |
Type of antimicrobial resistance (references: non-XDR and CSAB) | ||||||
Non-XDR versus XDR | ||||||
 Non-XDRh | 61 (58.1) | 20 (32.8) | 41 (67.2) | – | 5.03 | 0.02e |
 XDR | 44 (41.9) | 6 (13.6) | 38 (86.4) | 3.09 (1.12–8.51) |  |  |
CSAB versus CRAB | ||||||
 CSAB | 6 (5.7) | 6 (100) | 0 (0) | – | 19.33 | < 0.001e |
 CRAB | 99 (94.3) | 20 (20.2) | 79 (79.8) | – |  |  |
Appropriateness of the antimicrobial therapy (reference: appropriate) | ||||||
 Appropriate | 56 (53.3) | 23 (41.1) | 33 (58.9) | – | 17.13 | < 0.001e |
 Inappropriate | 49 (46.7) | 3 (6.1) | 46 (93.9) | 10.69 (2.96–38.57) |  |  |