Efficacy of an antimicrobial stewardship intervention for early adaptation of antibiotic therapy in high-risk neutropenic patients

Table 5 Clinical outcomes

Outcomes	Pre-intervention period (n = 56)	Intervention period (n = 57)	p value
Clostridioides difficile infection	2* (4)	0 (0)	0.243
ICU admission	5 (9)	5 (9)	1
Bacterial infection-related ICU admission	2 (4)	2 (4)	1
30-day mortality	0 (0)	3 (5)	0.243
Bacterial infection-related 30-day mortality	0 (0)	0 (0)	1
In-hospital mortality	2 (4)	3 (5)	1
Length of stay (days), median (IQR)	30.5 (27–41)	34 (29–39)	0.308

Data are presented as number (%) unless otherwise indicated
Abbreviations: ICU: Intensive care unit; IQR: Interquartile range
*One Clostridioides difficile infection occurred after neutrophil recovery and antibiotic discontinuation

ISSN: 2047-2994