Fig. 3

Genetic relationship of 191 study isolates (all first patient isolates and 33 additional subsequent isolates with differing MLST/cgMLSType) displayed as a circular midpoint rooted phylogenetic tree based on a Neighbor Joining Tree with distance based on MLST and cgMLST alleles. Read from inside to outside: The color of the inner circle and clade corresponds to a specific CT. CTs that were identified only once or twice are marked in white. In the first ring from inside isolates that are not first patient isolates but are included in this image as they differ in their MLST and/or cgMLSType are marked with a blue square. The next ring shows the 13 different sequence types which are marked with different colors. The outer ring of color strips shows the year of isolation, which visualizes the switch in the dominating STs and CTs over the years. The stars in the outer circle correspond to the resistance gene identified, thereby illustrating the dominance of vanB (red stars) in our study isolates and their preponderance for certain CTs