Table 3 Rates of substrate (β-lactam) hydrolysis and inhibitor profiles of Acinetobacter spp. isolated from the ICU of Afzalipoor Hospital.
Substrate | MIC (µg/mL) | β-lactamase inhibitor | Substrate hydrolysis (µmol) |
|---|---|---|---|
CTX | >240 | - | 80± 0.04 |
CTX | >240 | P-CMB (50mM) | 80.2± 0.02 |
CTX | >240 | NaCl (100mM) | 2.1± 0.01 |
CTX | >240 | Sulbactam (200µg/ml) | 10.2± 0.03 |
CTX | >240 | Clavulanic (200µg/ml) | 7.5± 0.02 |
CAZ | >240 | - | 80± 0.04 |
CAZ | >240 | P-CMB (50mM) | 80.2± 0.02 |
CAZ | >240 | NaCl (100mM) | 2.1± 0.01 |
CAZ | >240 | Sulbactam (200µg/ml) | 30.2± 0.03 |
CAZ | >240 | Clavulanic (200µg/ml) | 7.5± 0.02 |