Skip to main content

Table 1 Summary of reported mortality from literature

From: Mortality and Clostridium difficile infection: a review

Author Study type Country 30-day mortality Mortality at endpoint (other) Participants
Arvand, Hauri, Zaiss, Witte & Bettge-Weller (2009) Prospective multicentre Germany 25% - 41
Bhangu, Bhangu, Nightingale & Michael (2010) Cohort UK 38% - 158
Bishara, Peled, Pitlik & Samra (2008) Case control Israel 15% case - Total 217
    11.5% control (NS)   52 cases
Cadena et al. (2010) Cohort US 16% 29% at 90 days 129
Chung et al. (2010) Cohort Taiwan 23.3% 37.2% IHM 86
Cloud, Noddin, Pressman, Hu & Kelly (2009) Cohort US - 12.1% IHM 272
Dubberke et al. (2008) Case control US - 38% cases at 180 days Cohort = 18,050 390 cases
     12% non-cases at 180 days  
Fenner et al. (2008) Cohort Switzerland 9% - 78 cases
Gasperino et al. (2010) Cohort US 16% cases, 5% controls 20% cases IHM (cases) 216,108 cases
     8% IHM (controls)  
Gravel et al. (2009) Prospective multicentre Canada 16.3% - 1430
    5.7% attributable   
Gulihar, Nixon, Jenkins & Taylor (2009) Cohort UK 19% (cases) 67% cases at 180 days 170 cases
    9% match cohort 29% matched cohort at 180 days 3,247 matches
Karas, Enoch & Aliyu (2010) Review UK Not applicable Not applicable Not applicable
Kenneally et al. (2007) Cohort US 36.7% - 278
    6.1% attributable   
Labbe et al. (2008) Cohort Canada 23.9% - 230
Loo et al. (2005) Prospective multicentre Canada 24.8% - 1703
    6.9% attributable   
Lyytikainen et al. (2009) Cohort Finland - 14% at 30 days post-discharge 8 093
Marra, Edmond, Wenzel & Bearman (2007) Cohort US   17.2% at 14 days 58
     27.6% IHM  
McGowan et al. (2011) Cohort UK 35.5% 13.4% at 7 days 2,571
     20% at 14 days  
     58.7% at 1 year  
Musher et al. (2005) Prospective observational US - 27% at 90 days 207
Pant et al. (2010) Cohort US 13.6% - 184
Shears, Prtak & Duckworth (2010) Cohort UK 24.7% 30.0% at 90 days 227
Sundram et al. (2009) Case control UK 14.4% at 28 days (extrapolated) 11% at 3 days (027) 97 cases
     3% at 3 days (106) 97 controls
Wilson et al. (2010) Cohort UK 35.9% - 128
Zilberberg, Shorr, Micek, Doherty & Kollef (2009) Cohort. Secondary analysis of Kenneally et al. (2007) US 26.9% <65 years - 278
    45.2% >65   
  1. Note. IHM = in-hospital mortality.