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Table 1 Antibiotic resistance against eight antimicrobial agents, stratified for origin of the sample

From: Antimicrobial susceptibility profiles of human and piglet Clostridium difficile PCR-ribotype 078

 Antibiotic agent MIC 90(mg/L) Resistant isolates according to CLSIb(%)
Human n=49 Pig n=50 ECOFFa(mg/L) Breakpoint (mg/L) Human n=49 Pig n=50 Difference p-value
Amoxicillin 0.25 0.25 2 16 0 (0%) 0 (0%) 1.00
Cefuroxim ≥256 ≥256 - - NA NA NA
Clindamycin 2 2 ≥256 8 3 (6%) 1 (2%) 0.30
Erythromycin ≥256 ≥256 ≥256 8 29 (59%) 38 (76%) 0.07
Ciprofloxacin ≥32 ≥32 ≥32 8 46 (94%) 48 (96%) 0.044
Moxifloxacin 8 8 ≥64 8 8 (16%) 8 (16%) 0.067
Tetracycline 8 8 8 16 0 (0%) 0 (0%) 1.00
Imipenem ≥32 ≥32 8 16 14 (29%) 25 (50%) 0.03
  1. a ECOFF: Epidemiological cut-off value - The European Committee on Antimicrobial Susceptibility Testing (EUCAST).
  2. b CLSI: Clinical and Laboratory Standards Institute.
  3. NA: not applicable. This is stated because no breakpoint was determined by the CLSI and, therefore, the percentage of resistant isolates could not be determined.