Carbapenem-resistant K. pneumoniae trends from the European Antimicrobial Resistance Surveillance Network (EARS- Net), 2005 to 2010. Percentages and trends of invasive carbapenem-resistant K. pneumoniae isolates from European countries reporting to the European Antimicrobial Resistance Surveillance Network (EARS-Net) from 2005 to 2010. The 6 countries shown in this figure are those whose laboratories reported carbapenem susceptibility data in K. pneumoniae isolates for at least three years during 2005–2010, had a percentage of 1% or higher for any of these years and for which a significantly increasing or decreasing trend was observed. The number of countries with a percentage resistance of 1% or higher, increased from 2 in 2005 (Greece, 27.8%; Germany, 3.1%) to 5 in 2010 (Greece, 49.8%; Cyprus, 16.4%; Italy, 12.5%; Hungary, 5.9%; Portugal, 2.2%). Significant increasing trends were observed for Greece, Cyprus, Hungary and Italy (p < 0.01). Germany, which did not report any carbapenem-resistant K. pneumoniae isolate in 2010, showed a decreasing trend (p < 0.01).