Data were collected for 2883 BCS, including 2766 initial BCS. The kind of surgery was available for 2731 initial BCS: 1527 (56%) lumpectomies, 563 (21%) mastectomies, 143 (5%) and 170 (6%) immediate and secondary reconstructions, respectively, 35 (1%) node dissections, 293 (11%) breast mammoplasty surgeries.
The SSI incidence rate (median onset delay: 16 days) was 2.86%[CI95%: 2.27-3.55] (79 SSI) as compared to 4.1%[CI95%: 3.20-5.15] in 2008, corresponding to a 30% decrease. S. aureus was identified in 58 cases.
The multivariate analysis highlighted several factors related to the risk of SSI onset. A 3-4 ASA score (vs ASA 1) was associated to an adjusted odds ratio (ORa) of 2.51[1.21-5.18]). As compared to lumpectomies without node dissection and prophylactic antibiotics, immediate reconstructions were related to an ORa of 3.65[1.41- 9.42], node dissection without prophylactic antibiotics and associated or not to lumpectomy to an ORa of 4.58[2.13-9.87]. Hematoma and lymphocele punctures were respectively related to an ORa of 3.19[1.33-7.66] and 2.98[1.84-4.83]. No relation was noted for prior chemo/radiotherapy and for invasive preoperative procedures.