Overall, 57 residents (26.3%) were colonized with SA, 23 of the isolates (43.9%) were methicillin-resistant. There was 17 cases of infections with the Staphylococcus aureus aetiology, of which 10 (58.8%) were caused by MRSA (8 skin infections and 2 pneumonia). The average age for the population of whom 63.2% were female was 76.2 years. The MRSA prevalence in PPS was 11.9%, in CS - MRSA infection incidence was 5.2%. Factors associated with MRSA presence were: the general status of patients, limited physical activity, wound infections (odds ratio, OR 4.6), ulcers in PPS (OR 2.1), diabetes (OR 1.6), urinary catheterization (OR 1.6) and stool incontinence (OR 1.2). Prevalence of MRSA in the group of residents with limited physical activity was 65.8% (relative risk, RR 12.1). Results of the multivariate analysis showed that age, physical activity impairment and ulcers were significantly associated with the risk of occurrence of MRSA.