The following surveillance activities are currently carried out: monitoring of patients colonized with MRSA, including sampling and collection of new, non-endemic strains of MRSA, notably carrier of SCCmecII between 3/2011 and 12/2012; epidemiology and investigation of any new proven case of C. difficile infection; investigation of viral infection outbreaks (norovirus since 2008, and influenza since 2011). Compliance with hand hygiene practices is monitored since 2006. In addition, in 2012, we performed an evaluation on indicators of: correct disinfection of multiple-usage medical devices; correct application of specific isolation measures; environmental cleansing along the course of viral gastroenteritis clusters or C. difficile infection.