Twenty one needle stick injuries were documented in the last two years. Six of them were doctors and nurses, 4 were radiology technicians and 4 were ward assistants and 1 was a phlebotomist. Five episodes occurred on venepunture 4 were following biopsy and four while clearing clinical waste, 5 during line insertion .Four of the sources were positive for blood borne viruses, two were HIV positive one HCV and one hepatitis B. All the patients received Post exposure prophylaxis at the earliest (2 ART,1 Booster with Hepatitis B vaccine).None of them had seroconversion on follow up. Needle stick injuries occurred most commonly during radiological procedures (33.3%) and in the CCU (33.3%).