Of 261 suspected cases, 171 (65.5%) samples were positive for influenza A and 90 (34.5%) for influenza B. Among these cases (median age, 76 y [range, 1.5-100.5]), 122 (46.7%) were male. A total of 117 (44.8%) were treated with oseltamivir and 38 (14.5%) were treated >72 h from disease onset. Clinical complications are still under investigation. Among these, 43 (16.5%) required intensive care and 9 (3.5%) died. A total of 94 cases were NOSO (36.1%). Hospital stay before NOSO SI diagnosis was 4 d for 2 cases, and > 5 d for 92 cases. Recommended infection control procedures (droplet precautions with single room isolation whenever possible) were implemented for 230/261 patients (88.1%). Droplet precautions were applied for <3 days for 133/167 community-acquired SI (79.6%) cases and for 57/94 NOSO SI (60.6%). Among the NOSO SI, we observed 9 outbreaks involving 80 patients. Reliable information on vaccination status revealed that 53 patients were vaccinated. Healthcare workers’ vaccination status was low (~37%).