Introduction
A VRE Outbreak was declared November 2010 in a large community hospital impacting two acute care and two complex continuing care units. A number of infection control measures were immediately put into action with an ongoing focus on environmental controls, adherence to hand hygiene and isolation protocols. Despite concerted efforts to resolve the VRE outbreak in a timely fashion, ongoing transmission of VRE continued with three distinct peaks identified throughout the 17 month period. A total of 110 patients became colonized with VRE.