A total of 248 isolates including 9 different pathogens were included. Acinetobacter spp. was highly (70-90%) resistant to all tested antimicrobials including carbapenems (three- and four-class MDR prevalence were 86% and 78%, respectively). Pseudomonas aeruginosa was moderately (20-40%) resistant to all tested antimicrobials including antipseudomonal penicillins(three- and four-class MDR prevalence were 18% and 10%, respectively). With exception of ampicillin (fully resistant), Klebsiella spp. had low (0-14%) resistance to other tested antimicrobials with no detected MDR. Staphylococcus aureus was fully susceptible to vancomycin with 42% resistance to oxacillin. There were significant increasing trends of MDR Acinetobacter spp. but not Pseudomonas aeruginosa during the study.