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Table 2 Adjusted and unadjusted odds ratios with ESBL-EC bacteraemia as the dependent variable

From: Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study

  ESBL-EC (%) ESBL-KP (%) Crude OR (95% CI)d/P value Adjusted OR (95% CI)d
Demographics/acquisition
Male gendera 60/92 (65.2) 49/78 (62.8) 1.1 (0.6–2.2)  
Median age (IQR)a 65.5 (53–76) 61.5 (38.5-75.5) P = 0.01  
High prevalence countrya 35/92 (38.0) 8/78 (10.3) 5.4 (2.2–13.7) 4.3 (1.6–11.6)
Pacific Islander 10/92 (10.9) 14/78 (17.9) 0.6 (0.2–1.4)  
NZ Maori 2/92 (2.2) 6/78 (7.7) 0.3 (0.04–1.5)  
LTCF residence 11/92 (12.0) 8/78 (10.3) 1.2 (0.4–3.5)  
Community acquisitiona 35/92 (38.0) 6/78 (7.7) 7.4 (2.7–21.1) 7.9 (2.6–23.9)
Community onset infection 73/92 (79.3) 37/78 (47.4) 4.3 (2.1–8.8)  
Recent ICU admissiona 5/92 (5.4) 14/78 (17.9) 0.3 (0.08–0.8)  
Median hospital days (IQR) 1.5 (0–16) 9.5 (0–30.5) P <0.0001  
Hospital 1a 53/92 (57.6) 29/78 (37.1) 2.3 (1.2–4.5)  
Hospital 2a 21/92 (22.8) 32/78 (41.0) 0.4 (0.2–0.9) 0.3 (0.1–0.7)
Hospital 3a 18/92 (19.6) 17/78 (21.8) 0.9 (0.4–2.0)  
Source of bacteraemia
Urinary tract 49/92 (53.3) 33/78 (42.3) 1.6 (0.8–3.0)  
Gastrointestinal 17/92 (18.5) 10/78 (12.8) 1.5 (0.6–3.9)  
Central line 0/92 (1.1) 5/78 (7.7) P = 0.02  
Febrile neutropenia 6/92 (5.4) 13/78 (15.4) 0.3 (0.1–1.1)  
Prostate biopsy related 8/92 (8.7) 0/78 (0) P = 0.008  
Bone and joint 0/92 (0) 3/78 (3.8) P = 0.095  
Respiratory tract 6/92(6.5) 3/78 (3.8) 1.7 (0.4–9.2)  
Uncertainc 4/92 (4.3) 9/78 (11.5) 0.3 (0.1–1.3)  
Comorbidities
Diabetes 22/92 (23.9) 14/78 (17.9) 1.4 (0.6–3.3)  
Recurrent UTI 4/92 (4.3) 5/78 (6.4) 0.7 (0.1–3.0)  
Long term IDC 11/92 (12.0) 12/78 (15.4) 0.7 (0.3–2.0)  
Solid tumour 17/92 (18.5) 13/78 (16.7) 1.1 (0.5–2.7)  
Haematological malignancy 12/92 (13.0) 16/78 (20.5) 0.6 (0.2–1.4)  
Previous transplanta,b 1/92 (1.1) 7/78 (9.0) 0.1 (0.005–0.9) 0.06 (0.007–0.6)
Dialysis 4/92 (4.3) 2/78 (2.6) 1.7 (0.3–14.0)  
CPDa 14/92 (15.2) 4/78 (5.1) 3.3 (1.0–12.6) 5.5 (1.5–20.1)
Median number comorbidities (IQR) 1 (1–3) 1 (1–2) P = 0.39  
  1. aIndicates that variable was included in the multivariate analysis.
  2. b4 patients with liver transplants, and 4 patients with hematopoietic stem cell transplants transplants (one additional patient with a liver transplant had separate episodes of ESBL-EC and ESBL-KP bacteremia).
  3. cUncertain sources were those where the treating clinician was unable determine the aetiology.
  4. dP values are included in this column for continuous variables and dichotomous variables for which an OR could not be calculated.
  5. IQR, interquartile range; LTCF, long term care facility; UTI, urinary tract infection; IDC, Indwelling urinary catheter; CPD, Chronic pulmonary disease.