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Table 7 Studies describing hospital costs or charges in patients with resistant and multidrug-resistant Pseudomonas aeruginosa infections

From: Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis

Author

Study groups (n)

Description of cost

Hospital Inpatient Care Costs or Charges

Reported P-value

Ref

Main findings

Eagye et al. (2009)

Meropenem resistant P. aeruginosa (58)

Median total cost (IQR)

$100,704 ($27,710 – $183,125)

< 0.001

[53]

Meropenem susceptible P. aeruginosa (125)

$32,594 ($13,112 – $100,702)

Meropenem resistant P. aeruginosa (58)

$100,704 ($27,710 – $183,125)

< 0.001

Control (57)

$25,744 ($17,456 – $40,616)

Evans et al. (2007)

Susceptible P. aeruginosa (73)

Median total cost (IQR)

$99,672 ($43,714 – $187,260

0.015

[71]

Resistant P. aeruginosaa (47)

$69,502 ($24,853 – $113,933)

Gasink et al. (2006)

Fluoroquinolone resistant P. aeruginosa (320)

Median total charges (IQR)*

$62,325 ($22,129 - $188,979)

0.008

[64]

Fluoroquinolone susceptible P. aeruginosa (527)

$48,733 ($18,760 - $124,820)

Lautenbach et al. (2010)

Imipenem resistant P. aeruginosa (253)

Mean hospital cost after culture sampling (95% CI)

$286,417 ($234,326 – $338,510)

< 0.001

[63]

Imipenem susceptible P. aeruginosa (2289)

$189,274 ($172,428 – $206,121)

Morales et al. (2012)

MDR P. aeruginosab (134)

Mean hospital cost after culture sampling (median)

$13,178 ($5,745)

< 0.001†

[49]

Susceptible P. aeruginosa (149)

$4,258 ($2,420)

Resistant P. aeruginosa (119)

$10,662 ($5,248)

< 0.001†

Susceptible P. aeruginosa (149)

$4,258 ($2,420)

  1. *Hospital charges reported after identification of infection with P. aeruginosa; †P-value reported for mean length of stay; aAbsence of susceptibility to all the drugs in one or more of the following antibiotic classes: aminoglycosides, cephalosporins, carbapenems, and fluoroquinolones; bAbsence of susceptibility to carbapenems, β-lactams, quinolones, tobramycin, and gentamicin.